Silicon Valley-based SRI International has developed a missile MiSL algorithm to screen cancer genes.

When we talk about Silicon Valley, what are we talking about? Hewlett-Packard, Apple, Google, Facebook, Tesla, SpaceX's black technology, and small start-ups that pop into the public eye every few years.
fact, there is another group of mysterious geniuses who, in Silicon Valley's little-known non-profit research institutions, are changing our world in a low-key way with one study after another... SRI International is one such institution.
There have been countable star projects that were born here in the past and have been acquired or split up by large companies to set up a company: the invention of the basic raw materials for laundry detergents, check magnetic safety inks, mouse prototypes, inkjet printers, optical discs and LCD displays, and the realization of the world's first Internet communications... Even Siri, the smart assistant in Apple's operating system, started out as an in-house start-up for SRI International.
called the agency Silicon Valley's Whampoa Military Academy nothing more than ... SRI International's research interests also include medicine, where they are working on how to diagnose and fight cancer early! Previous research in the medical community has found that some cancers are controlled by pairs of genes A and B, known as synthetic lethals.
assuming that gene A lesions fail, B will expand the expression to compensate for the loss of A, maintaining the growth of cancer cells, and vice versa.
that if A and B can be lesions at the same time, the cancer cells they control will die and the cancer will stop spreading."
, the medical community began to use this theory to develop medicine and treatment solutions, but the results were not ideal - the threshold was to accurately confirm this pair of genetic relationships, like looking for a needle in a haystack.
SRI International's bioininscerology team, led by medical and computer expert and Stanford University researcher Subarna Sinha, has made a major breakthrough! The team developed a new computer algorithm called Mining Synthetic Lethals, MiSL.
new algorithm, the team screened 89 pairs of synthetic lethal genes for 12 different types of cancer, more than 3,100 cancer-related gene lesions, and hundreds of millions of genes.
, 17 of these pairs have been discovered before, put into clinical use or drug development - demonstrating the effectiveness of the MisL algorithm! At the Silicon Valley Technology Summit SYNC 2017 held last week at PingWest, Xin explained the new findings to hundreds of professionals present.
, MiSL can be used not only to identify potential synthetic death genes, but also to import new data sources for reverse validation, finding genes that lead to resistance to existing cancer drugs, expanding new research... The birth of the MiSL algorithm was a milestone in the war against cancer, Xin said.
miSL, in the future we may see more targeted cancer treatments for individual patients, or even a complete defeat of cancer one day...