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Sinopharm's dual-target RNAi candidate STP707 gets clinical approval in the U.S.

 Last Update: 2021-08-08
 Source: Internet
 Author: User

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Article source: Pharmaceutical Guanlan

On July 6, Sirnaomics announced that the company's small interfering nucleic acid (siRNA) candidate STP707 clinical trial application has been approved by the US FDA

RNA interference (RNAi) is a method of silencing genes through double-stranded RNA

According to the press release, STP707 is a siRNA drug with both anti-tumor and anti-fibrosis effects.

The overexpression of TGF-β1 and COX-2 play a key regulatory role in tumor formation

Previously, STP707 has been in preclinical non-human primate studies.

Note: The original text has been deleted

Reference materials:

[1] The RNAi drug candidate STP707 from Sinopharm was approved by the FDA for the phase I clinical IND for the treatment of solid tumors.

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