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▎Prostate cancer, edited by WuXi AppTec's content team, is a type of cancer unique to men and a "killer" that has plagued men around the world for thousands of years.
In the middle-aged male mummies of ancient Egypt, scientists have found prostate cancer tumors, and found that this cancer has spread throughout the body, affecting bones everywhere.
Today, when cancer is more and more raging, prostate cancer has become one of the most common cancers in men.
According to the latest global cancer burden data released by the World Health Organization’s International Agency for Research on Cancer (IARC) in 2020, the incidence of prostate cancer ranks second among all malignant tumors in men worldwide (about 1.
41 million), second only to lung cancer (about 144 The number of deaths (approximately 380,000) was ranked 5th among the deaths related to malignant tumors; among Chinese men, the number of cases of prostate cancer (approximately 120,000) and the number of deaths (approximately 50,000) ranked respectively among common male cancers.
6th and 7th place.
The occurrence of prostate cancer is related to many factors, among which genetics is one of the main factors.
Epidemiological studies have shown that if an immediate family member (brother or father) has prostate cancer, the risk of prostate cancer will increase by more than double; if two or more immediate family members have prostate cancer, the relative risk will increase to 5-11 times; patients with family history of prostate cancer are diagnosed about 6-7 years earlier than patients without family history.
Image source: 123RF So for people with genetic risk of prostate cancer, how can you reduce the risk of cancer? Recently, a study published at the 2021 annual meeting of the American Association for Cancer Research (AACR) may bring us the answer.
The results of the study show that adhering to a healthy life>
Researchers from Harvard School of Public Health and Harvard Medical School Brigham and Women's Hospital analyzed data from the US Health Professionals Follow-up Study (HPFS), involving a total of 10443 male subjects.
By analyzing 269 single nucleotide polymorphisms (SNPs) related to the risk of prostate cancer, the researchers calculated the subjects' prostate cancer polygenic risk score (PRS) to assess the genetic risk of prostate cancer.
The higher the score, the higher the genetic risk of prostate cancer.
At the same time, through the questionnaire researchers also collected the subjects’ life>
Specifically, for the following 6 life>
1) Never smoked or quit smoking for more than 10 years; 2) Body mass index (BMI) below 30 kg/m2; 3) At least 180 minutes of high-intensity exercise or 420 minutes of moderate-intensity exercise a week; 4) Eat at least a week 7 servings of raw tomatoes or tomato juice with corresponding nutrient content; 5) At least 1 serving of deep-sea fish per week, including mackerel, salmon, sardines and swordfish, etc.
; 6) Eat less than 3 servings of processed meat per week, including hot dogs , Bacon, sausage, etc.
(Note: The above 1 part is 65g.
) A total score of 1-2 points means that the life>
In addition, the researchers also counted the incidence and death of prostate cancer in the subjects during the study period.
Image source: During the average follow-up period of about 20 years, 123RF had 2111 cases of prostate cancer, of which 238 cases were fatal.
After adjusting for other factors, the researchers found that people with high genetic risk are more likely to develop prostate cancer; and adhering to a healthy life>
Compared with the 1/4 subjects with the lowest polygenic risk score for prostate cancer, the 1/4 subjects with the highest score were associated with a 439% increase in the risk of prostate cancer and a 243% increase in the risk of fatal prostate cancer.
Among the 1/4 subjects with the highest polygenic risk score for prostate cancer, compared with subjects with a life>
Since this study is an observational study, it only shows that following a healthy life>
Image source: 123RF study author, Dr.
Anna Plym from Harvard University School of Public Health pointed out that previous studies have found that exercise is a protective factor for fatal prostate cancer, and that exercise can help reduce the risk of fatal prostate cancer.
However, the mechanism of the impact of other healthy life>
For people with genetic risk of prostate cancer, Dr.
Plym suggests that they should be screened in time, because they have a higher risk of cancer.
Early detection and early treatment will likely cure prostate cancer.
At the same time, they should follow a healthy life>
China's "Prostate Cancer Screening Expert Consensus" also recommends that people at high risk of prostate cancer should carry out serum PSA (prostate specific antigen) testing as soon as possible.
High-risk groups include: men over 50 years old; people over 45 years old with a family history of prostate cancer Males; males aged> 40 years old with baseline PSA> 1 μg/L.
Of course, a healthy life>
It is recommended to read Asymptomatic Hyperuric Acid Is Not Itchy? Eating this way keeps you away from gout! Can the heart get cancer? Have you heard of heart tumors? Demystifying why the heart is not susceptible to cancer.
Pigs, cattle, sheep, and processed meat eat more.
What is the harm to the heart? These studies understand how good cells become cancerous and form tumors? After reading this content, you will understand that whether you have high blood pressure, high cholesterol, or diabetes, doing this well will help reduce cardiovascular risk.
Reference materials [1] Healthy Life>
If you need guidance on treatment plans, please go to a regular hospital for treatment.
In the middle-aged male mummies of ancient Egypt, scientists have found prostate cancer tumors, and found that this cancer has spread throughout the body, affecting bones everywhere.
Today, when cancer is more and more raging, prostate cancer has become one of the most common cancers in men.
According to the latest global cancer burden data released by the World Health Organization’s International Agency for Research on Cancer (IARC) in 2020, the incidence of prostate cancer ranks second among all malignant tumors in men worldwide (about 1.
41 million), second only to lung cancer (about 144 The number of deaths (approximately 380,000) was ranked 5th among the deaths related to malignant tumors; among Chinese men, the number of cases of prostate cancer (approximately 120,000) and the number of deaths (approximately 50,000) ranked respectively among common male cancers.
6th and 7th place.
The occurrence of prostate cancer is related to many factors, among which genetics is one of the main factors.
Epidemiological studies have shown that if an immediate family member (brother or father) has prostate cancer, the risk of prostate cancer will increase by more than double; if two or more immediate family members have prostate cancer, the relative risk will increase to 5-11 times; patients with family history of prostate cancer are diagnosed about 6-7 years earlier than patients without family history.
Image source: 123RF So for people with genetic risk of prostate cancer, how can you reduce the risk of cancer? Recently, a study published at the 2021 annual meeting of the American Association for Cancer Research (AACR) may bring us the answer.
The results of the study show that adhering to a healthy life>
Researchers from Harvard School of Public Health and Harvard Medical School Brigham and Women's Hospital analyzed data from the US Health Professionals Follow-up Study (HPFS), involving a total of 10443 male subjects.
By analyzing 269 single nucleotide polymorphisms (SNPs) related to the risk of prostate cancer, the researchers calculated the subjects' prostate cancer polygenic risk score (PRS) to assess the genetic risk of prostate cancer.
The higher the score, the higher the genetic risk of prostate cancer.
At the same time, through the questionnaire researchers also collected the subjects’ life>
Specifically, for the following 6 life>
1) Never smoked or quit smoking for more than 10 years; 2) Body mass index (BMI) below 30 kg/m2; 3) At least 180 minutes of high-intensity exercise or 420 minutes of moderate-intensity exercise a week; 4) Eat at least a week 7 servings of raw tomatoes or tomato juice with corresponding nutrient content; 5) At least 1 serving of deep-sea fish per week, including mackerel, salmon, sardines and swordfish, etc.
; 6) Eat less than 3 servings of processed meat per week, including hot dogs , Bacon, sausage, etc.
(Note: The above 1 part is 65g.
) A total score of 1-2 points means that the life>
In addition, the researchers also counted the incidence and death of prostate cancer in the subjects during the study period.
Image source: During the average follow-up period of about 20 years, 123RF had 2111 cases of prostate cancer, of which 238 cases were fatal.
After adjusting for other factors, the researchers found that people with high genetic risk are more likely to develop prostate cancer; and adhering to a healthy life>
Compared with the 1/4 subjects with the lowest polygenic risk score for prostate cancer, the 1/4 subjects with the highest score were associated with a 439% increase in the risk of prostate cancer and a 243% increase in the risk of fatal prostate cancer.
Among the 1/4 subjects with the highest polygenic risk score for prostate cancer, compared with subjects with a life>
Since this study is an observational study, it only shows that following a healthy life>
Image source: 123RF study author, Dr.
Anna Plym from Harvard University School of Public Health pointed out that previous studies have found that exercise is a protective factor for fatal prostate cancer, and that exercise can help reduce the risk of fatal prostate cancer.
However, the mechanism of the impact of other healthy life>
For people with genetic risk of prostate cancer, Dr.
Plym suggests that they should be screened in time, because they have a higher risk of cancer.
Early detection and early treatment will likely cure prostate cancer.
At the same time, they should follow a healthy life>
China's "Prostate Cancer Screening Expert Consensus" also recommends that people at high risk of prostate cancer should carry out serum PSA (prostate specific antigen) testing as soon as possible.
High-risk groups include: men over 50 years old; people over 45 years old with a family history of prostate cancer Males; males aged> 40 years old with baseline PSA> 1 μg/L.
Of course, a healthy life>
It is recommended to read Asymptomatic Hyperuric Acid Is Not Itchy? Eating this way keeps you away from gout! Can the heart get cancer? Have you heard of heart tumors? Demystifying why the heart is not susceptible to cancer.
Pigs, cattle, sheep, and processed meat eat more.
What is the harm to the heart? These studies understand how good cells become cancerous and form tumors? After reading this content, you will understand that whether you have high blood pressure, high cholesterol, or diabetes, doing this well will help reduce cardiovascular risk.
Reference materials [1] Healthy Life>
If you need guidance on treatment plans, please go to a regular hospital for treatment.
