Special issue of SLAs discovery: application status of high throughput flow cytometry in drug development

July 24, 2018 / BIOON / - a special issue of SLAs discovery introduced the latest application of high-throughput flow cytometry (HTFC) in drug development Alexandre Chigaev, The special issue of University of New Mexico is co edited by Dr Mei Ding of AstraZeneca and Dr Bruce S Edwards of the University of New Mexico It contains a series of research papers, application instructions and technical instructions, reflecting the latest progress of HTFC in method design, providing professional views and prospects for a series of applications of HTFC in drug development For example, for different software And description of data analysis process, evaluation of relative advantages and disadvantages of different platforms of biological reaction of interest, new HTFC application of biopharmaceuticals and new antibodies, new drug development of targeted or mechanism mediated, application of HTFC in single cell analysis, engineering of autologous T cells to express chimeric antigen receptor for adoptive cell therapy of cancer, etc Flow cytometry has been proved to be a powerful technology, which can analyze single cells and granules with multiple parameters, and is widely used in a series of clinical, basic and applied researches, including identification and analysis of cell surface and intracellular proteins, DNA, cell proliferation, cell activity, intracellular particle size and cell size Reference: high throughput flow cytometry in drug discovery