Steady magnetic fields lower blood sugar in diabetic mice

"Hold your mouth and open your legs" is a six-word maxim for diabetics, and new research suggests that "magnetic field exposure" could be a new boon for diabetics.
in a paper published online January 6 in Innovation, Zhang Xin, a researcher at the Center for Strong Magnetic Field Science at the Hefei Institute of Material Sciences of the Chinese Academy of Sciences, studied mice with type II diabetes (T2DM) using a steady-state magnetic field, and after two weeks, the mice's ante rate decreased by 23.2%. Further mechanism studies have found that stable magnetic fields regulate blood sugar levels mainly by altering iron metabolism in mice and reducing islet β cell oxidative stress levels.
It is learned that the team used ferrite boron permanent magnets to design four different magnetic field strength, direction and distribution of stable magnetic field, from week 5 on the mouse cage continuously placed in the magnetic field and fed a high-fat diet, and at 11 weeks injection of streptococcal to induce high blood sugar model (blood sugar value ≧11.1 mmol/L). Streptococcus is a DNA alkylation reagent that selectively destroys islet β cells of certain species of animals and can induce diabetes in many animals.
results found that four magnetic fields had different effects on T2DM mice, with the effect of a moderate-strength steady-state magnetic field in the downward direction being most pronounced: after two weeks, the average blood sugar in mice dropped from 12.02 mmol/L to 9.23 mmol/L. In addition, the magnetic field treatment can reduce weight gain, significantly reduce fatty liver and tissue damage and other symptoms.to further explore the mechanism of hypoglycemia, the researchers explored intestinal microorganisms, tissue testing and in-body cell experiments. The results showed that the magnetic field could affect the redelocation of iron in islet β cells and their gut microorganisms in mice, reduce oxidative stress levels of islet cells, and relieve symptoms of high blood sugar.
T2DM is the most important type of diabetes, accounting for 90%. According to the ninth edition of the 2019 Global Diabetes Survey published by the International Diabetes Federation, about 116 million people aged 20 to 79 in China have diabetes, with a prevalence rate of 10.9%, which is a common "popular disease".
, U.S. scholars used a steady-state magnetic field generated by electromagnetic irons to join an electric field and process it for seven hours a day, reducing an empty stomach blood sugar by 33 percent in mice on a high-fat diet after 30 days. Zhang Xin said that permanent magnets compared to electromagnet electric field has a low cost, high safety, simple technology and no maintenance and many other advantages, the future may be used as an easy physical method to treat diabetes.
but she also suggests that large-scale, double-blind, controlled clinical studies are needed to find the best magnetic field conditions for human T2DM treatment, as different magnetic field parameters can lead to different outcomes.
fact, "magnetic therapy" as an intervention has always been controversial: unclear scientific mechanisms, irregular research, inadequate clinical trials, placebo effects and so on. In this regard, Zhang Xin said, "magnetic therapy" mechanism is complex and the effect is more moderate, often can not be immediate, but in recent years, not only the use of pulsed magnetic field transcranial magnetic stimulation has been approved for clinical use, and there is more and more experimental evidence that health intervention based on steady-state magnetic field also has good application prospects, should be carried out more systematic research. (Source: Chen Huanhuan, China Science Journal)
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