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A scientist from The University of Science and Technology in Australia is working on a study that could bring us one step closer to 3D bioprinting of human tissue for transplantation and regeneration.
project, led by PhD student Lilith Caballero Aguilar, involves developing a way to control the speed and frequency of growth factor release, which is critical to the development and survival of implanted stem cells.
in other words, when a 3D bioprinted stem cell structure is implanted, it can take up to six weeks to convert into certain types of cells, such as cartilage.
slow release of growth factors in order for stem cells to convert.
to do this, Caballero Aguilar is developing polymer materials that can be used as a release mechanism for growth factors.
is said to be using an emulsification process that quickly shakes water and oil to produce tiny "microballs" in the solution that can be cross-linked to produce a material suitable for controlling growth factors.
participants in the study included members from BioFab3D and ACMD.
BioFab3D - ACMD is the first bioengineering laboratory to operate in an Australian hospital, jointly established by the University of Science and Technology, the Royal Melbourne Polytechnic University, the University of Melbourne, the University of Wollongong and St Vincent's Hospital in Melbourne, where the laboratory is located.
in this laboratory context, Caballero Aguilar works closely with orthopaedic surgeons and muscle specialists at the hospital to advance her research in a practical way.
currently, the BioFab3D-ACMD Laboratory is working on two major bioengineering projects: one focusing on cartilage regeneration and the other on repairing and regenerating damaged muscle fibers.
study of 3D bioprinting by Cabalero Aguilar could have a real impact on both projects.
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