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The weather is cold in autumn and winter, and the temperature difference between morning and evening is large, which is the season of high incidence of intracranial aneurysm rupture
.
As one of the common cerebrovascular diseases , cerebral aneurysm makes arterial vessels more prone to rupture, and has the characteristics of high prevalence, high rupture rate, and high mortality and disability rate
Vascular cerebral aneurysms make arterial blood vessels more prone to rupture, and have the characteristics of high morbidity, high rupture rate, and high mortality and disability rate
15% of patients will die directly, and about 70% of patients may have a second rupture, at which time the fatality rate accounts for 60%-70%
The researchers searched Embase and Pubmed for articles published before December 1, 2020
.
PHASES score (population, hypertension , age, aneurysm size, early subarachnoid hemorrhage in another aneurysm, aneurysm site), smoking, and positive family history of aneurysm subarachnoid hemorrhage using Cox proportional hazards regression models Adjusted to compare rupture rates in women with men
hypertension
Finally, individual patient data from 9 cohorts were pooled, with a total of 9940 patients (6555 women, 66%) with 12193 unruptured intracranial aneurysms and 24357 person-years of follow-up
.
Rupture occurred in 163 women (rupture rate 1.
Overall, compared with men, women were older (61.
9 vs 59.
5 years), less likely to smoke (20% vs 44%), had internal carotid aneurysms more often (24% vs 17%), arterial Tumor size was larger (≥7 mm, 24% vs 23%)
.
Women had a 43% higher risk than men (HR=1.
Overall, compared with men, women were older (61.
In conclusion, women have a higher risk of aneurysm rupture than men, and this gender difference cannot be explained by differences in patient- and aneurysm-related risk factors for aneurysm rupture
.
.
In conclusion, women have a higher risk of aneurysm rupture than men, and this gender difference cannot be explained by differences in patient- and aneurysm-related risk factors for aneurysm rupture
references:
Sex Difference and Rupture Rate of Intracranial Aneurysms: An Individual Patient Data Meta-Analysis.
Sex Difference and Rupture Rate of Intracranial Aneurysms: An Individual Patient Data Meta-Analysis.
https://doi.
org/10.
1161/STROKEAHA.
121.
035187 Leave a comment here
