Stroke: Tiantan Hospital: The new diffusion imaging score can effectively predict the prognosis of acute basilar artery stenosis

Acute basilar artery occlusion (BAO) is a catastrophic medical condition that accounts for 1% of all ischemic strokes and 5% of large vessel occlusive strokes

In the BEST trial (acute basilar artery occlusion

In the BASILAR trial (EVT treatment of acute basilar artery occlusion study), the authors found that the ratio of EVT and 90-day mRS score ≤ 3 was significantly higher; nevertheless, this trial is a single-arm design, and selection bias is inevitable

In this way, Lian Liu and others of Tiantan Hospital, based on clinical experience and previous literature, developed a new medulla-midbrain (PM) and thalamus (PMT) score based on diffusion-weighted imaging (DWI)

They reviewed eligible patients who received endovascular treatment for acute basilar artery occlusion

While evaluating the PMT score, it also evaluated the early computer tomography score and brainstem score for the prognosis of acute stroke in the posterior circulation

A total of 107 pre-treatment MRI patients were included in this cohort

In the good outcome group, the early prognosis of acute stroke in the posterior circulation had a higher computed tomography score, which was not statistically significant

The results of ROC curve analysis showed that the early computed tomography score for the prognosis of acute stroke in the posterior circulation was less accurate for a good prognosis (area under the curve, 0.

In addition, favorable PMT score <7 (probability ratio, 22.

The important significance of this study lies in the discovery that in patients with acute basilar artery occlusion after endovascular treatment, the PMT score based on diffusion-weighted imaging before treatment shows good prognostic value for clinical results