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Together, they implanted a harmless bacteria gene into the nose, keeping it in the nose and triggering an immune response
The results of the study published in the journal Science Translational Medicine show that people have a strong immune response to the bacteria that cause meningitis
Meningitis occurs in all age groups, but mainly affects infants, young children, and the elderly
About 10% of adults carry Neisseria meningitidis in the back of the nose and throat without any signs or symptoms
The "friendly" bacterium N.
The new data builds on the team’s previous work and aims to take advantage of this natural phenomenon
For those people, Lactam N.
The research team gave it one of the key weapons of Neisseria meningitidis; a "sticky" surface protein that adheres to cells on the lining of the nose
These modified bacteria can not only induce a stronger immune response, but also survive longer
The results of this study, funded by the Medical Research Council, offer hope for this new method of preventing life-threatening infections without the need for drugs
Dr.
"Theoretically, it is possible to express any antigen in our bacteria, which means that we can adjust them to combat multiple infections that enter the human body through the upper respiratory tract
Professor Reid, the director of the Biomedical Research Center at the National Institutes of Health in Southampton, said: "This study shows that using nasal drops containing genetically modified bacteria can protect people from serious diseases
Journal Reference :
Jay R.