Studies show that high salt intake can change the intestinal flora of mice

Recently, a study published in nature reported that high salt intake can change the intestinal flora of mice In view of the increasing recognition of the role of intestinal microflora in diseases, the above findings highlight the potential of intestinal microflora as a potential therapeutic target against salt sensitive diseases In order to determine the effect of high salt intake on the composition of intestinal flora, German researchers analyzed (http:// fecal samples of mice fed salt divided into normal and high salt food The results showed that by the 14th day, there was a significant reduction in a variety of microorganisms in mice fed high salt food After that, they used 16S ribosomal DNA sequencing and computational methods to identify the most important reduced flora, and found that Lactobacillus murinus had the strongest association with high salt food The results showed that the injection of Lactobacillus murinus into mice could reduce Th17 cells and prevent the development of salt induced exacerbation of experimental autoimmune encephalomyelitis and salt sensitive hypertension Another small pilot study in healthy (http:// humans found that increased salt intake reduced the survival of a variety of lactobacilli bacteria, along with an increase in Th17 cells and a rise in blood pressure, consistent with the above results.