Studies have found that smokers and non-smokers have different mutation patterns behind lung cancer
About 10% to 25% of lung cancers occur in non-smokers; however, most of the genome sequencing studies on lung cancer use tumors from smokers
Maria Teresa Landi of the National Cancer Institute and colleagues sequenced 232 lung cancer patients who had never smoked in the past (average age at diagnosis was 64.
The researchers also found that the study failed to find a strong genetic signature related to smoking, even for individuals who had been exposed to secondhand smoke
Although the study needs to be repeated in a larger patient array to clearly describe these results, Landi et al.
Related paper information: https://doi.
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