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    Home > Medical News > Medical Science News > Su Bing's research team discovered a new type of intestinal stromal cells

    Su Bing's research team discovered a new type of intestinal stromal cells

    • Last Update: 2021-03-18
    • Source: Internet
    • Author: User
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    Su Bing's research team discovered a new type of intestinal stromal cells
    Su Bing's group discovered new intestinal stromal cells Su Bing's group discovered new intestinal stromal cells

    On March 4th, Beijing time, the international academic journal "Nature" published the research work of Professor Su Bing's research group at Shanghai Institute of Immunology, Shanghai Jiaotong University School of Medicine in the form of Research Article-"MAP3K2-regulated intestinal stromal cells define a distinct stem cell niche".


    And the mechanism provides new ideas for intestinal repair and regeneration and clinical treatment of diseases.


    Figure 1.


    Figure 1.


    Intestinal stromal cells have long been considered to be a relatively simple functional cell that lacks heterogeneity.


    This study by Professor Su Bing’s group first found that the evolutionary conserved Thr/Ser protein kinase MAP3K2 can play a key protective role against DSS-induced enteritis in mice by maintaining the number and function of Lgr5+ stem cells in the intestinal tract.


    Figure 2.


    Figure 2.


    Figure 3.


    Figure 3.


    Zhong Gong

    This research is the result of the concerted efforts of Professor Su Bing's team, and it is also the first project carried out by Professor Su Bing to join the Shanghai Jiao Tong University School of Medicine after leaving Yale University and returning home.


    Related paper information: org/10.


    org/10.
    1038/s41586-021-03283-y" target="_blank">https://doi.
    org/10.
    1038/s41586-021-03283-y
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