Recently, the Institute of Biotechnology of the Chinese Academy of Agricultural Sciences and the Beijing Institute of Animal Husbandry and Veterinary Medicine have successfully created corn germplasm with high astaxanthin.
According to Chen Rumei, the corresponding author of the paper, astaxanthin is a kind of carotenoid, which is usually found in marine organisms such as algae, shrimp and crab.
The research used the "source-sink-flow" strategy of synthetic biology to design the astaxanthin metabolic pathway, by increasing the synthesis of lycopene, and using RNAi technology to guide the conversion of lycopene to β-carotene, using seed specificity The sexual bidirectional promoter drives the β-carotene hydroxylase gene and β-carotene ketonease gene to extend the carotenoid synthesis pathway to astaxanthin synthesis in corn kernels.
The high astaxanthin corn germplasm content created by this method reached 47.
After using this high anthocyanin corn germplasm to feed laying hens, 12.
The study also established an astaxanthin morphology detection method, which can analyze the three astaxanthin isomers of trans, 9-cis and 13-cis in corn and egg yolk at one time.
The research results reflect the effectiveness and malleability of biotechnology in creating nutritional fortification products that are beneficial to human health, and the created nutritional fortification products have broad application prospects.
Related paper information: org/10.
org/10.
1111/pbi.
13593" target="_blank">https://doi.
org/10.
1111/pbi.
13593
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