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Caffeine—1,3,7-trimethylxanthine—is one of three common alkaloids found in coffee, cola nuts, tea, cacao beans, mate, and other plants. The other two are theophylline and theobromine (
1
). The effects of caffeine are commonly reported to be as a stimulant of the central nervous system, cardiac muscle, and the respiratory system. It is also a common diuretic and delays fatigue (
1
). It has also been reported (
1
) that caffeine in combination with an analgesic, for example, aspirin, can be used in the treatment of headaches. However, there are few data to substantiate its efficacy in this role.