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The accurate and complete gene annotation map of the new coronavirus is completed

 Last Update: 2021-05-20
 Source: Internet
 Author: User

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Confirmation of protein coding genes and analysis of mutations in mutant strains

The accurate and complete gene annotation map of the new coronavirus is completed

Confirmation of protein coding gene analysis of mutant strains Mutation confirmation of protein coding gene analysis of variant strains Mutation confirmation of protein coding gene analysis of mutations of variant strainsAccurate and complete gene annotation map of the new coronavirus complete The precise and complete gene annotation map of the new coronavirus is completed

Science and Technology Daily, Beijing, May 11 (Reporter Liu Xia ) Scientists from the Massachusetts Institute of Technology wrote in the journal Nature Communications published on the 11th that after conducting extensive comparative genomics research, they mapped out the new crown The most accurate and complete gene annotation map of the virus to date has confirmed several protein-coding genes, and it has also been found that some genes do not code for any protein.

Liu Xia

The genome of the new coronavirus is composed of nearly 30,000 RNA bases.

In order to determine these protein-coding genes, an experimental team led by Professor Manolis Chris of the Computer Science and Artificial Intelligence Laboratory used the computational technology developed by itself to analyze the new crown virus, the SARS virus and 42 strains of the bat Sabe virus subgenus Analyzed.

The results showed that in addition to the discovery of 5 genes previously found in other coronaviruses, Chris' team also confirmed 6 protein-coding genes in the new coronavirus genome, while the other 5 genes believed to code for proteins did not have this ability.

In addition, Chris' team also analyzed more than 1,800 mutations that have appeared since the new coronavirus was first discovered, and compared the evolution speed of each gene in the past and the evolution speed since the outbreak.

The researchers also analyzed mutations in several variants of the new coronavirus-B.

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