The Applications of 3-Chloro-6-(piperidin-3-yloxy)-pyridazine hydrochloride, 98+% C9H13Cl2N3O, MW: 250.12

3-Chloro-6-(piperidin-3-yloxy)-pyridazine hydrochloride, also known as 3-CPO, is a pharmaceutical intermediate used in the synthesis of certain medications.
It is a white to off-white, crystalline solid with a molecular weight of 250.
12 and a melting point of 230-232°C.
The compound is highly soluble in water, methanol, and ethanol, but relatively insoluble in dichloromethane and ethyl acetate.
3-CPO has a wide range of applications in the pharmaceutical industry due to its ability to inhibit certain enzymes and its potential as an anti-inflammatory and analgesic agent.

One of the most common applications of 3-CPO is as an inhibitor of the enzyme phosphodiesterase 1 (PDE1).
PDE1 is involved in the degradation of cGMP, a molecule that plays a crucial role in smooth muscle relaxation and blood flow regulation.
By inhibiting PDE1, 3-CPO can increase the levels of cGMP and improve smooth muscle relaxation, leading to benefits such as reduced blood pressure and improved cardiovascular health.

In addition to its effects on smooth muscle, 3-CPO has also been shown to possess anti-inflammatory and analgesic properties.
It is able to inhibit the production of pro-inflammatory cytokines and reduce the expression of inflammatory genes, making it a potential treatment for inflammatory conditions such as rheumatoid arthritis.
3-CPO has also been shown to reduce pain in animal models, making it a potential treatment for chronic pain conditions.

3-CPO is also used as a building block in the synthesis of certain medications.
For example, it can be converted into SL652494, an investigational drug for the treatment of inflammatory and cardiovascular diseases.

The use of 3-CPO in the pharmaceutical industry is not limited to the above-mentioned applications.
It is also used as a research tool for studying the biology of smooth muscle cells, and as a pharmacological tool for studying the function of various enzymes and signaling pathways.

In conclusion, 3-Chloro-6-(piperidin-3-yloxy)-pyridazine hydrochloride, is a versatile compound with a wide range of applications in the pharmaceutical industry.
Its ability to inhibit certain enzymes and its potential as an anti-inflammatory and analgesic agent make it a valuable tool in the development of new treatments for a variety of diseases.
Its use as a building block in the synthesis of certain medications also underscores its importance in the pharmaceutical industry.
With ongoing research, 3-CPO's potential applications and benefits for human health will continue to be explored.