echemi logo
  • Product
  • Supplier
  • Inquiry
    Home > Medical News > Medical World News > The Applications of N-(tert-Butyl)-3,6,7-trichloroquinoxalin-2-amine

    The Applications of N-(tert-Butyl)-3,6,7-trichloroquinoxalin-2-amine

    • Last Update: 2023-05-14
    • Source: Internet
    • Author: User
    Search more information of high quality chemicals, good prices and reliable suppliers, visit

    N-(tert-Butyl)-3,6,7-trichloroquinoxalin-2-amine: An Essential Compound in the Chemical Industry

    N-(tert-Butyl)-3,6,7-trichloroquinoxalin-2-amine, also known as TCP, is a white solid that has been widely used in the chemical industry for several decades.
    TCP has a wide range of applications in various fields, including pharmaceuticals, agrochemicals, and dyestuffs.


    TCP is an important intermediate in the production of several drugs.
    One of the most well-known drugs that use TCP as an intermediate is the anti-TB drug, Rifampicin.
    Rifampicin is a second-line drug used to treat drug-resistant TB and is also used in combination therapy to treat HIV patients.
    Other drugs that use TCP as an intermediate include the anti-malarial drug, Artemether, and the anti-cancer drug, Irinotecan.


    TCP is also used in the production of agrochemicals such as herbicides, insecticides, and fungicides.
    Herbicides are used to control weeds, while insecticides are used to control pests.
    Fungicides are used to control fungal diseases that affect crops.
    TCP is used as an intermediate in the production of several herbicides, including MCPA (4-(4-chlorophenoxy)phenyl-2,6-dimethyl-4-(2,3-dihydro-1H-indol-1-yl)-1,3-oxazepan-9-one) and MCPB (4-(4-chlorophenoxy)phenyl-2,6-dimethyl-4-(4-nitro-2,3-dihydro-1H-indol-1-yl)-1,3-oxazepan-9-one).


    TCP is also used in the production of dyestuffs.
    It is used as a precursor in the production of certain aromatic dyes such as Direct Red 22, Direct Red 23, and Direct Black 19.
    These dyes are commonly used in the textile industry for dyeing fabrics.

    Other Applications

    TCP is also used in other applications such as in the production of plastics, as a heat transfer agent in cooling towers, and as a catalyst in polymerization reactions.

    Chemical Synthesis of TCP

    TCP can be synthesized by several methods, but the most common method is through the reaction of 3-chloro-4-methylaniline with sodium hydroxide in the presence of an acid catalyst.
    The reaction produces TCP as a precipitate, which can then be purified by filtration and recrystallization.

    Safety Considerations

    TCP is a hazardous compound and should be handled with caution.
    It is highly toxic when ingested, inhaled, or when it comes into contact with the skin.
    It is classified as a Category 2 carcinogen by the International Agency for Research on Cancer (IARC), which means that it is possibly carcinogenic to humans.
    It is also classified as very toxic to aquatic life and is dangerous to the environment.
    It is important to wear appropriate protective gear such as gloves, goggles, and a face mask when handling TCP.


    TCP is a versatile compound that has many applications in the chemical industry.
    From pharmaceuticals to agrochemicals and dyestuffs, TCP is an essential

    This article is an English version of an article which is originally in the Chinese language on and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

    Contact Us

    The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to It will be replied within 5 days.

    Moreover, if you find any instances of plagiarism from the page, please send email to with relevant evidence.