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Source: Academic bi-sulfur, also known as alcohol-free sulfur, is a classic old drug that has been approved by the U.S. FDA for the treatment of chronic alcohol addiction for more than 50 years.
patients who were originally alcoholic, during the period of taking bi-sulphate, a little drinking will produce a strong feeling of discomfort, thus establishing a negative reflex of drinking, to achieve the purpose of abstaining from alcohol.
some drugs (such as some antimicrobials), if drinking during the drug, will also occur with bithylitoma similar effects, called "double thiopenum-like reaction", light makes people blush, abdominal pain vomiting, serious may cause acute heart failure and even death.
many health-conscious friends familiar with a word, called "cephalosporine with wine, say go on", said that this is the truth, and double thiopental used to stop drinking principle is similar.
but the use of bision itself has long been proven to be safe and has some anti-inflammatory effects.
interestingly, scientists recently discovered that the classic drug seems to have surprising new uses.
animal experiments showed that obese middle-aged mice quickly lost weight to normal levels after taking bithyluzole, and problems caused by fat build-up to the liver, islet, etc. improved.
related findings published in cell Metabolism, a sub-journal of Cell.
specifically, the scientists first fed middle-aged mice high fat for months.
as expected, the mice not only gained weight, but also began to have metabolic problems, such as insulin resistance, elevated fasting blood sugar levels, and so on, similar to prediabetes.
next, the researchers divided the experimental animals into four groups, fed them to a standard rat grain, a high-fat diet, high-fat foods with small doses of bithyl sulphon, and high-fat foods with high doses of bithiles (converted to a person's dosage by weight, equivalent to a maintenance dose). After
time, mice that changed to standard rat food gradually returned to normal in terms of weight, fat, blood sugar levels, etc., while mice on a high-fat diet continued to gain weight, and as fat builds up, metabolic problems become more and more serious, these are not surprising.
however, the changes in mice taking dithnosolwere surprised scientists.
despite still eating high-fat foods and not getting smaller, they didn't gain weight, they dropped sharply.
mice, especially those in the large-dose bisulfurum group, lost up to 40 percent of their body weight in just four weeks, the same as their peers who switched to standard rat food.
"When we saw the data showing that the mice were losing weight and getting thinner and thinner, we couldn't believe our eyes.
" said Dr. Michel Bernier, the study's lead author.
in addition to becoming thinner, blood sugar levels improved significantly in both groups of mice taking bithyliazole.
the researchers then examined the animals' organ tissue and found that fat tissue actually decreased after the fat mice continued to take bisulphony, after problems such as liver fat degeneration and islet cell hyperpluse caused by a high-fat diet were reversed. The de-lipid reduction effect and metabolic improvement of
bithilitonos were also experimentally proven in obese rats.
researchers say these positive results may be derived from the anti-inflammatory properties of bithyliosulprate, which help ediac blood sugar imbalances, protect them from high-fat diets and weight gain, and improve metabolic efficiency.
the study, the experimental animals continued to take dithilionine for a long time without any adverse reactions.
but the team stressed that these are based on animal studies and that it is not possible to infer potential benefits for humans.
they recommend not using bithylsulberen for weight management outside the scope of clinical trials.
of course, with these new findings, the researchers say they are planning future research steps to reveal the potential for bibuthode to treat obesity, including setting up a controlled clinical trial to test whether it can help obese and metabolically abnormal lying patients lose weight, and to conduct more in-depth research into the drug's molecular mechanisms and potential for binding to other therapeutic interventions.
we look forward to further research into this classic old drug.
.