The establishment of toxicological evaluation criteria will lead to the marginalization of Chinese Medicine

The common goal of Chinese and Western medicine is to improve the efficacy of drugs, avoid and reduce side effects With the progress of science and technology and the improvement of living standards, the research on pharmaceutical ingredients, pharmacology and toxicology is more precise and demanding The relevant parties have formulated a unified standard, which requires that even for drugs without obvious side effects, indications, dosage, time, method, taboo, etc should be indicated, as is the case with Chinese and Western drugs For example, there are many over-the-counter drugs in Chinese patent medicines In order to prevent and reduce toxic and side effects, it is necessary to have detailed drug instructions that are easy for patients to understand Of course, it is not easy to study the toxicology of traditional Chinese medicine Its four Qi, five flavor, ups and downs are closely related to the theory of TCM viscera and pathogenesis, and the medical theory and pharmacology are consistent, which is far from the expression form of modern pharmacology Ancient doctors divided traditional Chinese medicine into three categories, i.e top, middle and bottom, or five categories with toxic and non-toxic effects They usually thought that there were more toxic and side effects of bottom In clinical practice, the ancients summed up the 18 anti and 19 dreads of the compatibility of traditional Chinese medicine, formulated the processing, compatibility requirements and medication taboos to reduce toxicity, and reasonably avoided and reduced the toxic and side effects of traditional Chinese medicine under specific historical conditions; at the same time, the toxic reaction of traditional Chinese medicine may be the manifestation of its pharmacological effect, such as arsenic trioxide (the main ingredient) in the treatment of leukemia Some drugs containing mercury can calm, disinfect, and promote the production of skin and sore All of the above make the research more difficult However, the cruelty of reality has taught us a lesson: Houzao price powder contains aristolochic acid, which can cause irreversible renal damage if taken for a long time; Niuhuang price antidote pill (tablet) contains realgar price, which may accumulate toxicity; Liuwei Dihuang price pill contains Alisma price, which has been proved to be hepatotoxic and nephrotoxic by experiments, so these Chinese patent medicines have been rejected by European and American countries But in contrast, some Western medicines with prominent and serious side effects are often used, such as aspirin, penicillin, etc., because they can clearly clarify pharmacology, toxicology, side effects, and use taboos Over the years, there have been calls for "establishing the evaluation standard of curative effect of traditional Chinese medicine in accordance with the characteristics of traditional Chinese medicine" and "establishing the evaluation standard of toxicology of traditional Chinese medicine" But the author wants to say that reducing the evaluation of toxicology of traditional Chinese medicine for any reason or trying to establish another standard will undoubtedly lead to the marginalization of traditional Chinese medicine, which is not conducive to the development of traditional Chinese medicine and the world To serve the people of the world, traditional Chinese medicine should not only meet the domestic standards, but also meet the international standards.