The first DNA vaccine has been approved, making it easier to produce and store. Is this the future of vaccines?

In December 2020, the U.

mRNA vaccines are considered to be the future of vaccinology due to their high efficiency, safety, high production efficiency, and low cost

We all know that according to the central law, mRNA is responsible for transmitting the genetic information stored in DNA and directing protein synthesis in cells

In fact, there are currently more than 10 DNA COVID-19 vaccines in clinical trials worldwide

The first DNA vaccine

A few days ago, India urgently authorized and approved a new DNA coronavirus vaccine.

This DNA Covid-19 vaccine is called ZyCoV-D and was developed by Zydus Cadila in India.

DNA Covid-19 vaccine is being developed globally

Domestic DNA vaccine research and development company

In addition to this DNA vaccine urgently authorized by India, the DNA vaccine developed by Inovio and its Chinese partner company Ai Diweixin-INO-4800 is the fastest and most concerned

Ai Di Weixin was founded in 2009.

At the end of April 2021, Ai Di Weixin submitted a listing application to the main board of the Hong Kong Stock Exchange.

Ai Di Weixin R & D pipeline

Will DNA vaccines be the future?

Since the 1990s, both DNA vaccines and mRNA vaccines have been under development

It is understood that the DNA used in the ZyCoV-D vaccine is a circular DNA strand, which encodes the spike protein (S protein) of the new coronavirus and a promoter sequence that initiates gene expression

The Indian drug regulatory authority urgently authorized the approval of the ZyCoV-D vaccine for vaccination of people aged 12 years and over.

As the first DNA vaccine, ZyCoV-D vaccine is of great significance, which shows that we have a new type of vaccine

DNA is easier to synthesize than mRNA, so it is easier to produce and lower in cost, and DNA is more stable, so it is easier to store and transport