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    Home > Biochemistry News > Biotechnology News > The genetic force of life is not more than 7%, and the gene has little effect on the length of life.

    The genetic force of life is not more than 7%, and the gene has little effect on the length of life.

    • Last Update: 2020-08-06
    • Source: Internet
    • Author: User
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    In the long river of time, people's pursuit of longevity has never stopped.
    from refined health to the search for longevity gene, new ideas are constantly put forward, but have been overturned.
    in a recent group of genealogy analyses of more than 400 million people, researchers have again come up with a new idea: while longevity tends to persist in the family, the effect sonings on longevity are much lower than previously estimated and not as large as one might think. In the study, "Estimates of the Heritability of Human Life For life, " said lead author Graham Ruby in the study, "We can potentially learn a lot about the biology of aging from human genetics, but if the genetic force spent on life is low, it lowers our expectations of what we can learn and its ease of use."

    " genetic forces are an indicator of the degree of variation in a particular trait, such as longevity.
    correspond to non-genetic factors such as lifestyle, sociocultural factors and accidents.
    previous estimates of human life expectancy were between 15 and 30 percent.
    Ruby works for Calico Life Sciences, a company that studies aging biology, led by Catherine Ball, the company's chief scientist, who works with scientists at ancestry, a genealogy website, using open genealogy data from Ancestry.com to estimate the genetic forces of human lifespan.
    before sharing the data with the Calico team, Ancestry stripped all the identifiable information from the system, leaving only the year of birth, the year of death, the place of birth, and the family relationships that make up the family tree structure itself, and eventually established a family that included more than 400 million Americans of European descent, each connected through parent-child or spouse-spouse relationships.
    , the team then assessed the genetic strength of the family by examining the similarity in life span sons.
    researchers used a combination of mathematical and statistical modeling to focus on relatives born in the 19th and early 20th centuries.
    they found that siblings and cousins had roughly the same genetic value as previously reported.
    But, as observed in previous studies, they note that spouses' life spans are often related, and in fact they are more similar than siblings of the opposite sex.
    researchers suspect that this association between spouses may be due to living in a common family environment; the life expectancy of
    siblings and cousins is related, although they are not blood relatives and do not share a family, suggesting that factors other than genetic or environmental factors are at work.
    without a common genetic background and no common family, what is the biggest possible reason for the life-long similarity between people with these types of relationships? Back in the original data set, the researchers again analyzed the lifetime correlations of other, more remote relationship types and tested for alternative mating.
    "Here, selective mating means something important to longevity, and spouses tend to be very similar."
    Ruby explains, "in other words, people tend to choose a partner with similar characteristics to them, which can be understood as a partner who lives longer."
    "Of course, no one can easily guess the life span of a potential partner."
    generally speaking, people get married before either person dies, and because they can't predict someone's lifespan, human choice to mate must be based on other characteristics.
    may be based on genetic or socio-cultural, or both.
    ": "To give a non-gene example, if income affects longevity, the rich tend to marry other rich people, which leads to related life spans, and the same happens in more genetically controlled traits: for example, if tall people like tall mates and height is somehow related to your longevity, it exaggerates the genetic power of life expectancy.
    " the authors added.
    finally, by correcting the effects of these selection matings, the new analysis found that the genetic strength of life may not be more than 7%, or even lower.
    Source: Biological Exploration.
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