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The Guo Bin research group of the School of Basic Medical Sciences found that human cord blood functional hematopoietic stem cells were cultured in vitro under stress conditions...

 Last Update: 2021-09-11
 Source: Internet
 Author: User

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Hematopoietic stem cell transplantation is currently one of the most mature and effective stem cell treatments

August 31, 2021, Guo Bin Research Group , School of Basic Medical Sciences, Shanghai Jiaotong University School of Medicine, Hal E.

Researchers first found that after short-term in vitro culture of human cord blood hematopoietic stem cells, functional hematopoietic stem cells in a certain number of cord blood CD34+ cells were significantly reduced

This study identified the markers of functional hematopoietic stem cells under stress conditions in vitro culture and many potential hematopoietic stem cell self-renewal regulators, enriched the theoretical system of human hematopoietic stem cell biology, and provided a screening method for the expansion of human hematopoietic stem cells in vitro Effective targets for activators

Chen Yandan, a doctoral student at Shanghai Jiaotong University School of Basic Medicine, Fang Shuyi, a doctoral student at Indiana University School of Medicine, Dr.

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