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    Home > Biochemistry News > Microbiology News > The gut bacteria are also a natural defense system for our bodies.

    The gut bacteria are also a natural defense system for our bodies.

    • Last Update: 2020-09-30
    • Source: Internet
    • Author: User
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    Health is not only without disease, real health refers to a person in the physical, mental and social aspects are in a good and optimal state, on the one hand, the human system has good physiological function, on the other hand, the resistance to disease is strong, can adapt well to changes in the environment and various pathogenic factors on the body stimulation. True health is protected by a range of natural defense systems within the body that work from birth to the last day of life, keeping our cells and organs functioning properly., we discussed our angiogenesic defense systems and regenerative defense systems. Angiogenesy is the formation of new blood vessels to feed our organs as a health defense, while the regenerative defense system is responsible for organ growth and maintenance.See:There may be micro-tumors in everyone, and healthy angiogenesic defenses prevent them from growingthe body has the ability to self-renew cells to look at our regenerative defense systemsin fact, our bodies are not a single entity, but a highly complex microbial ecosystem that contains trillions of microorganisms that number well more than our own cells, or about 1.5-2 kg, equivalent to the weight of the brain. Most microorganisms are good for us, they are amazingly resilient and resistant to stomach acid and chemicals in the gut.Although the medical community once considered microbes to be feared vectors of disease that should be removed, disinfected and killed with antibiotics, we now know that most of the bacteria in our bodies work in highly complex ways to protect our health and even affect our behavior. Healthy bacteria are by no means passive overlords, but reciprocally co-living with us, forming a complex biological system that interacts with our cells and organs in many ways. Among them, the most concerned is the gut microorganisms.we learn a lot about gut microbes every day from researchers around the world about how they promote health and even help fight diseases such as cancer. Some gut bacteria, such as Lactobacillus lactobacillus and Bifidobacteria, have endocrine or hormone functions and can even produce and release neurotransmitters in the brain, including oxytocin, 5-oxycodone, gamma-aminobutyric acid and dopamine. These chemicals activate brain signals and profoundly affect our moods. Some bacteria release metabolites that protect us from diabetes, while others control the growth of belly fat. Our gut bacteria can also affect angiogenesis, stem cells and immunity; they can even affect our hormones, sexual health and social behavior; they can nourish our own cells and can also cause inflammation. Our gut bacteria can even determine our lives and deaths, whether we have disease or fight it.food has an amazing ability to affect our gut bacteria, which in turn can affect our health. After all, what we eat, bacteria eat. They metabolize the foods we eat, producing beneficial or harmful by-products that affect our health. We can use our gut microbial defense system to prevent and treat diseases.the relationship between humansbacteria, humans and bacteria evolved together on Earth. In the early days of Homois 300,000 years ago, our hunter-gatherer ancestors ate foods they could find, including grains, nuts, legumes and fruits, all of which contained large amounts of fiber, the food on which beneficial microbes depended. Food is carefully selected from bacteria-filled soil and plants, so every bite our ancestors ate was filled with microbes from the environment and eventually entered their intestines. Even after the first agricultural revolution in 10,000 D.D., when humans stopped hunting and gathering and relied on grown food, they were largely plant-based. This diet is rich in microbial-like fibers and is full of bacteria from the environment that have evolved to shape the bodies on which we depend.the fate of humans and bacteria are closely linked, for most of history humans did not even know about the presence of bacteria, let alone the role of healthy bacteria in our bodies. But over the centuries, science has changed our understanding of how bacteria cause disease and health. In the early days of microbiology, much of what we knew about bacteria focused on "bad" bacteria., throughout history, devastating epidemics have swept the world, killing tens of millions of people indiscriminately. Terrible diseases such as typhoid fever, plague, dysentery and leprosy are rampant, bringing suffering and death to countless people. Doctors at the time had only theories about the causes of these diseases, and they didn't even know that the unsothy surrounding environment would allow bacteria to spread. During that time, in most parts of the world, faeces, urine, rotting food and pests piled up on the streets, creating ubiquitous pits where bacteria could breed and spread.major breakthrough in the history of american medicine came in 1861, when Vienna experienced a high maternal mortality rate and an alarming number of women died of infection after giving birth at an obstetric clinic. Ignaz Semmelweis, a doctor at the clinic, noted that many doctors performed pathological autopsies on the dead mother before examining the woman, or contacted the next woman without thoroughly cleaning her hands and instruments after a pathological autopsy. Semmelweis wanted to know what killed those mothers and whether they would be taken back by doctors to find new victims. He came up with the bold idea that doctors should wash their hands with a "sterilization" solution between an autopsy and a maternal birth to eliminate the threat. This trick did work, and the maternal mortality rate from infection plummeted to single digits.. Semmelweis's findings are a critical moment in the development of health care procedures. In the next important milestone, Joseph Lister warns that hand washing is not enough, and that all surgical instruments must also be disinfected with a chemical solution, resulting in a reduction in gangrene after surgery. Innovations like these have led to high standards of cleanliness and sterilization in hospitals, operating rooms and doctor's offices that we take for granted today, and continue to save millions of lives., however, had an unintended consequence. The more people know about how to control and eliminate bacteria that can cause infection, the more common the idea that all bacteria are harmful, and the more they begin the era of bacterial phobia and continue to this day. Most of us grow up scrubbing, disinfecting and avoiding bacteria as much as possible. "Bacteria are harmful and need to be eliminated with antibiotics," a familiar message that has permeated public health and public awareness. Disinfectants, antibacterial hand sanitizers and antibacterial soaps are household commodities; In fact, the antibiotic revolution revolution revolutionized modern medicine, largely eliminating the most devastating epidemics of the past by sterilization that gave doctors, hospitals and public health offices around the world the ability to save lives., however, science has quietly made changes, and some bacteria are actually good for health. As early as 1907, Russian microbiologist Mechnikov began to question the possibility that "all bacteria are harmful". During the cholera epidemic in France in 1892, Mechnikov discovered that some bacteria might stimulate the growth of cholera, but to his surprise, others stopped it. This led him to speculate on whether ingesting some types of beneficial bacteria might help prevent deadly diseases. He was even more alarmed that some people lived longer, despite poor rural conditions, poor sanitation and poverty. He pointed out that in Bulgaria, there are farmers living in the Caucasus mountains for more than 100 years. He observed that the oldest villagers were drinking fermented yogurt containing Bulgarian Lactobacillus. Therefore, Mechnikov believes that one of the secrets of longevity is to eat healthy bacteria. Now it turns out that he is right. Intestinal bacteriosomes Now, the study of gut microbes is considered one of the most exciting and groundbreaking areas of medical research, and research is growing rapidly, changing our understanding of health and the way the food, supplement, pharmaceutical and diagnostic testing industries will produce products in the future. a lot about gut microbes, we've covered a lot of them before, and today we're going to highlight some of the insights from current cutting-edge research that will help us make better dietary choices. You've probably heard of line bacteria, Bacillus, thick-walled bacteria, Lactobacillus, metamorphosis. . . but they're just the beginning. It is estimated that there are more than 1 billion bacterial species in the world. The vast majority have no direct relationship with humans, but many other species have evolved to thrive within our bodies. There are more than a thousand known gut bacteria. More than 500 bacteria have been found in the human mouth, and each person usually has 25 or more bacteria in their mouth. A milliliter of saliva contains up to 100 million oral bacteria. , inspired by the Human Genome Project, the National Institutes of Health launched the Human Microbiome Program in 2008 to understand the mysteries of the human microbiome. The program published a landmark paper in 2012 in the prestigious scientific journal Nature documenting the microbiome in 242 people. The study examined bacteria in multiple parts of each volunteer's body on different occasions, including the mouth, nose, skin, intestines and reproductive tract. The researchers found that not only did the number and diversity of species in the microbiome vary widely between individuals, but there were also significant differences in bacteria in different parts of the same body. No set of bacteria is common to everyone, even to healthy people. diversity of the microbiome is an important sign of health, and the diversity of bacterial ecosystems brings strength and more effective collaboration to protect our health. The more bacteria we have, the healthier we will become. Our symbicological microbiome is an ecosystem that relies on a delicate balance among its members, who tolerate each other and work together for the sake of our health. our microbiome affects our health in many ways, including the substances they produce when processing food that passes through the gut. The most famous is a bacterial metabolite called short-chain fatty acids, which are by-products of gut bacteria digesting dietary fiber. By the way, the "probiotics" we often hear about are usually the dietary fiber that provides food for gut bacteria that produce short-chain fatty acids. Short-chain fatty acids have been found to have a surprising range of health functions: they protect the gut and overall health through anti-inflammatory properties; they improve our body's ability to metabolize glucose and lipids; and they can also improve immunity, guide angiogenesty, and help stem cells act as a bridge between the body's other four health defense systems. Lactobacillus lactobacillus and Bifidobacteria are both considered beneficial because they produce short-chain fatty acids. acetic acid, propyate and butyric acid are the three main short-chain fatty acids, which play a unique role in the body. For example, acetic acid is released into peripheral tissues, stimulating the production of leptin, which suppresses hunger; propionate lowers cholesterol, reduces inflammation, prevents the formation of atherosclerotic plaques and improves the health of the digestive system; and it activates immune cells; butyric acid, the main source of energy for colon cells, promotes colon health and has anti-inflammatory effects, and stimulates angiogenesis to promote wound healing and lead stem cells into different types of organs. other microbial metabolites can also promote health. For example, Plant Lactobacillus can produce metabolites that stimulate the anti-inflammatory response of intestinal stem cells, which can relieve irritation in the intestines and lay the foundation for intestinal healing. A study of Kimchi in South Korea has found that it contains plant Lactobacillus, a bacterial product that prevents influenza A. Ligatin is a kind of plant polyphenols, which have the role of probiotics. They are metabolized by gut microbes to produce bioactive substances called enterodols and intestinal esters, which have been shown to inhibit the development of breast cancer. Methylphenol and horse uric acid are also metabolites produced in the intestines and can reduce stress and anxiety. Researchers at the University of Eastern Finland have found that a diet rich in whole grains and dietary fiber causes bacteria to produce pyridine, another metabolite that prevents type 2 diabetes. , of course, there is a bad side to the fact that some of the substances produced by our gut microbes can also be toxic, so our goal should be to limit their production. For example, bacteria like Vibrio desulfurization produce hydrogen sulfide, a compound that smells like rotten eggs and is highly toxic to our guts. When Vibrio desulfurization produces too much hydrogen sulfide, it destroys the inner walls of the intestines, which can cause leaks in the intestines and make it easier for food particles and waste from the intestines to pass through the walls of the intestines into the bloodstream. Leaks from food particles can cause inflammatory reactions around the intestines, may produce allergic reactions to food, and may even cause colitis. Not surprisingly, hydrogen sulfide-producing bacteria have been found in the faeces of patients with inflammatory bowel disease. formation of intestinal bacteria and all over our bodies, especially the skin and body cavity. Health-promoting bacteria live in our teeth, gums, tongue, tonsils, nose, lungs, ears, reproductive tract, and especially intestines. is a hollow, long tube that starts in our mouth and ends in our anus, including the esobeer, stomach, small intestine and colon. The colon has the highest density of our microbiome. Inside the intestines, there is a layer of viscous mucus that protects the intestines. This mucus layer forms a barrier that blocks the harmful substances we eat or digest, as well as gut bacteria. Both the mucus layer and the intestinal wall may be affected by gut bacteria. Some bacteria actually multiply in mucus. The intestine is not just a simple digestive organ, it is also a health command center controlled by microorganisms. healthy bacteria in our guts may have existed before we were born. We usually think of a pregnant mother's uterus as sterile, and healthy bacteria only enter the baby's body when the baby's head is squeezed out of the birthing aisle. In the mother's vagina.
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