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The He Ming team of the School of Basic Medical Sciences reveals new mechanisms and new therapeutic targets for alcoholic liver disease?

 Last Update: 2021-10-20
 Source: Internet
 Author: User

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On October 12th, the team of Professor Ming He from the Department of Pathophysiology and the Key Laboratory of Cell Differentiation and Apoptosis of the Ministry of Education, Shanghai Jiaotong University School of Medicine, published an online publication titled "SIRT2-mediated deacetylation and deubiquitination of C/EBPβ prevention" in Cell Discovery.

Sirtuin 2 (SIRT2) is a member of the silent information regulator (sirtuin) protein family.

The study started from clinical analysis and found that the expression of SIRT2 protein in liver samples of ALD patients was significantly negatively correlated with the severity of ALD

Professor Ming He and Professor Qian Zhao of Shanghai Jiaotong University School of Basic Medicine are the co-corresponding authors.

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