The infectious power is comparable to chickenpox "Delta". Why is it so poisonous?

In recent days, the epidemic situation has rebounded severely in many parts of the country, and the prevention and control situation is grim

The head of the World Health Organization (hereinafter referred to as WHO) said on July 30 local time that the number of confirmed cases and deaths caused by new coronary pneumonia continued to rise globally, mainly due to the highly contagious new coronavirus Caused by the mutant strain Delta

Why is Delta so "poisonous"? What kind of mutation does it have? How infectious is it?

Delta virus load exceeds 1,000 times the original strain

Dr.

Rochelle Varensky, director of the US Centers for Disease Control and Prevention (CDC), said that new research shows that people who have been infected with the Delta strain and also vaccinated carry a lot of the virus in their noses and throats

The Los Angeles Times reported on July 30 that people infected with the Delta strain had 1,000 times more virus particles in the upper respiratory system than people infected with the original new coronavirus that caused the pandemic in the first place

On the severity, the Van Hoff stressed that in some countries under the influence of variants of the virus, the number of hospitalizations has increased, "but we have not seen a rise in disease death rates"

The P681R mutation makes the Delta strain more susceptible to infecting cells

Dr.

The website of "Nature" magazine published an article on July 28 that the outer surface of each new coronavirus particle is dotted with 24-40 randomly arranged spike proteins, which is the key to its binding with human cells

Delta strain has many mutations in the S1 subunit, including 3 mutations in RBD

According to the American Society of Microbiology, another mutation (located on a unique spike protein) in a place called the furin cleavage site may also make it easier for the virus to infect cells

There is evidence that a mutation in Delta called "P681R" promotes furin-mediated cleavage of the spike protein, accelerates the fusion of viral cells and human cells, and enhances the virus’s ability to neutralize antibodies.

Delta is as infectious as chickenpox

The Washington Post quoted an internal report from the CDC on July 30, stating that the delta mutant strain of the new coronavirus is as contagious as chickenpox

According to the report, this variant is also more likely to break through the protection of the vaccine on the human body

The report cited recent unpublished data obtained from the epidemic investigation, combined with data from external research, that people infected with the Delta strain and vaccinated may be as likely to spread the virus as people who have not been vaccinated

CNN reported on July 30 that a research team from the British infectious disease modeling agency stated that data showed that the transmission rate of the delta variant virus was 40%-60% higher than that of the alpha variant virus

Chi Chunhui, director of the Center for Global Health at Oregon State University in the United States, said that for the previous variants, it takes about 6 days for a person to produce enough virus to infect others after the initial infection, and the delta variant shortens the timeline to only 4 Day, so that it can spread in the community at an unprecedented speed

Vaccination is still a response

No vaccine is 100% effective
.
Therefore, despite being vaccinated, there are still more cases of breakthrough infections (i.
e.
infected persons who have completed vaccination)
.
The latest CDC study on July 30 showed that 74% of the infected people in the outbreak of the new crown in Massachusetts in the United States have been fully vaccinated
.

The CDC stated that it needs to continuously monitor the effectiveness of the vaccine against the variant virus
.
Tests conducted in a laboratory petri dish indicate that, theoretically, the immune response generated by the vaccine should be strong and broad enough to deal with the delta variant
.

CNN reported that infectious disease experts generally believe that the solution to the spread of Delta variants and other viruses is more vaccination
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"If more and more people are vaccinated, we will win this fight against the epidemic,
" Varensky said
.

Dr.
Van Khoff of the World Health Organization reminded that although there are some data indicating that people who are vaccinated may be infected and spread this mutant virus, this possibility is greatly reduced after the second dose of the vaccine is fully effective.

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She also said that the delta variants are not specifically targeted at children.
As long as the mutant virus is still spreading, they will infect anyone who has not taken proper precautions
.