-
Categories
-
Pharmaceutical Intermediates
-
Active Pharmaceutical Ingredients
-
Food Additives
- Industrial Coatings
- Agrochemicals
- Dyes and Pigments
- Surfactant
- Flavors and Fragrances
- Chemical Reagents
- Catalyst and Auxiliary
- Natural Products
- Inorganic Chemistry
-
Organic Chemistry
-
Biochemical Engineering
- Analytical Chemistry
-
Cosmetic Ingredient
- Water Treatment Chemical
-
Pharmaceutical Intermediates
Promotion
ECHEMI Mall
Wholesale
Weekly Price
Exhibition
News
-
Trade Service
Introduction
2-(Trifluoromethyl)pyrimidine, commonly referred to as TFP, is a synthetic organic compound that is widely used in the chemical industry.
It is a white to off-white solid with a slightly fruity odor, and it is soluble in water and many organic solvents.
TFP is used in a variety of applications, including as a pharmaceutical intermediate, a pharmaceutical excipient, a flavoring agent, and as a building block for the synthesis of other chemicals.
In the chemical industry, the production and use of TFP are subject to a number of regulations and guidelines.
These regulations are intended to ensure that the production, handling, and use of TFP are safe for workers, the environment, and the general public.
In this article, we will discuss the instructions for the safe use and handling of TFP in the chemical industry.
Hazard Identification
TFP is a hazardous substance, and it is subject to the requirements of the Controlled Substances Act (CSA) in the United States.
Under the CSA, TFP is classified as a Schedule 3 controlled substance, which means that it has a moderate potential for abuse and is subject to certain production, handling, and dispensing requirements.
TFP is also classified as a Category 3 carcinogen by the International Agency for Research on Cancer (IARC), which means that it is not classifiable as to its carcinogenicity to humans based on limited evidence of carcinogenicity in humans and sufficient evidence of carcinogenicity in experimental animals.
TFP is also classified as a Category 2 respiratory sensitizer by the IARC, which means that it is not classifiable as to its ability to cause asthma based on inadequate evidence.
Safety Precautions
The safe use and handling of TFP requires the following precautions:
- Wear appropriate personal protective equipment (PPE), including gloves, safety glasses or goggles, and a lab coat or other appropriate protective clothing.
- Handle TFP in a well-ventilated area, and avoid inhaling the vapors or dust.
- Avoid contact with skin, eyes, or clothing.
In the event of contact, rinse the affected area with plenty of water and seek medical attention if necessary. - Do not eat, drink, or smoke in areas where TFP is being handled.
Wash hands thoroughly after handling TFP. - Store TFP in a cool, dry, well-ventilated area, away from sources of heat, ignition, or strong oxidizing agents.
- Store TFP in a secure location to prevent unauthorized access or theft.
- Dispose of TFP and its waste products in accordance with local regulations and guidelines.
Handling and Storage
The safe handling and storage of TFP requires the following procedures:
- Ensure that the area where TFP is being handled is well-ventilated and free from sources of ignition or heat.
- Wear appropriate PPE, including gloves, safety glasses or goggles, and a lab coat or other appropriate protective clothing.
- Handle TFP in a clean, dry, and well-ventilated area.
Avoid creating dust or vapor when handling TFP. - Store TFP in a cool, dry, well-ventilated area, away from sources of heat, ignition, or strong oxidizing agents.
- Store TFP in a secure location to prevent unauthorized access or theft.
- Do not store TFP in a container that is not compatible with the material.
- Use appropriate packaging materials to ensure that TFP is properly contained during transport.
- Dispose of TFP and its waste products in accordance with local regulations and guidelines.
Purification and Character