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    Home > Medical News > Medical World News > The Instruction of Ethyl-5-bromopyrimidine-2-carboxylate

    The Instruction of Ethyl-5-bromopyrimidine-2-carboxylate

    • Last Update: 2023-05-05
    • Source: Internet
    • Author: User
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    Ethyl 5-bromopyrimidine-2-carboxylate is an organic compound that is commonly used in the chemical industry as a raw material for the production of a range of chemicals, drugs, and other products.
    The compound is typically synthesized through a multi-step process that involves the use of various chemical reagents and catalysts.

    One of the most common methods of synthesizing Ethyl 5-bromopyrimidine-2-carboxylate involves the use of water as a solvent and potassium hydroxide as a catalyst.
    The reaction involves the treatment of 5-bromo-2-nitro-1H-pyrimidine with ethyl bromide in the presence of water and potassium hydroxide.
    The reaction proceeds through a sequence of steps, including the formation of ethyl nitrite, which then undergoes a diazotization reaction to form ethyl hydrazide.
    The hydrazide is then converted into a carboxylate through a reaction with carbon dioxide, which is liberated from ethylene carbonate.
    The resulting carboxylate is then treated with sodium chloride to remov

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