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    Home > Biochemistry News > Biotechnology News > The new recombinant H7N4 avian influenza virus can lead to severe human infection.

    The new recombinant H7N4 avian influenza virus can lead to severe human infection.

    • Last Update: 2020-08-08
    • Source: Internet
    • Author: User
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    August 30, the reporter learned from Changzhou City CDC, Changzhou City, Jiangsu Province, has previously found the world's first case of H7N4 avian influenza.
    a new type of recombined H7N4 avian influenza virus was found and confirmed in respiratory samples from this case of severe pneumonia by a cooperative team from the Jiangsu Provincial Center for Disease Control and Prevention, the National Center for Disease Control and Prevention and the Institute of Microbiology of the Chinese Academy of Sciences.
    this is the first time that the H7N4 avian influenza virus has been confirmed to cause serious human infections.
    , the results of the study have been published in the journal Science Bulletin.
    early January 2018, Changzhou City Third People's Hospital, through the Changzhou City Unexplained Pneumonia Surveillance Network, sent a sample of patients with severe pneumonia to Changzhou CDC.
    by the Jiangsu Province CDC testing, confirmed changzhou disease control test results, and by genetic sequencing testing, determined to be a suspected influenza virus H7N4 subtype, the subtype has not been reported before the global human infection case.
    ", "Out of caution, Changzhou CDC has done a lot of treatment and investigation work against this case."
    observed the case for up to one month.
    ," said Dr. Chen Cong, deputy director of Changzhou CDC.
    study shows that this is the first time that the H7N4 avian influenza virus has been confirmed to cause serious human infections.
    epidemiological investigation and molecular trace analysis, the virus is likely to originate from wild birds, through the infection of patients in the wild poultry, and then spread across species to humans.
    sequence analysis found that the virus tends to bind to alpha-2, 3 receptors, is sensitive to low pathogenicity in poultry and sensitivity to neuraminidase inhibitors. further genetic evolution analysis of the virus
    suggests that the h7 gene of the virus came from the Eurasian wild birds, not from the H7N9 virus.
    experts believe that the discovery of this case is only a case, the public need not worry too much.
    .
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