echemi logo
Product
  • Product
  • Supplier
  • Inquiry
    Home > Active Ingredient News > Drugs Articles > The Production Process of 1H-Imidazole-4-carboxaldehyde,5-(1,1-dimethylethyl)-(9CI)

    The Production Process of 1H-Imidazole-4-carboxaldehyde,5-(1,1-dimethylethyl)-(9CI)

    • Last Update: 2023-05-12
    • Source: Internet
    • Author: User
    Search more information of high quality chemicals, good prices and reliable suppliers, visit www.echemi.com

    1H-Imidazole-4-carboxaldehyde, also known as 1H-Imidazole-4-carboxaldehyde,5-(1,1-dimethylethyl)-(9CI), is a key intermediate in the production of various chemicals and pharmaceuticals.
    The process of producing this compound involves several steps, each of which is carefully designed to ensure the maximum yield of the desired product while minimizing the formation of unwanted byproducts.


    The first step in the production of 1H-Imidazole-4-carboxaldehyde,5-(1,1-dimethylethyl)-(9CI) is the preparation of the starting material, which is typically 2-methylimidazole.
    This compound is synthesized by a variety of methods, including the reaction of 2-methylaniline with sodium hydroxide, followed by treatment with hydrogen chloride.


    Once the starting material is prepared, it is subjected to a series of reactions that involve the formation of a Grignard reagent, which is a reactive intermediate used in the synthesis of various organic compounds.
    The Grignard reagent is prepared by treating the starting material with magnesium metal in the presence of a solvent, such as ether or THF.
    The reaction typically takes place at low temperatures, and the resulting Grignard reagent is carefully stored and handled, as it is highly reactive and can undergo a variety of reactions.


    The next step in the production process is the reduction of the Grignard reagent, which is typically accomplished using hydrogen gas in the presence of a catalyst, such as palladium on barium sulfate.
    This reduction process converts the Grignard reagent into the desired aldehyde, which is then purified and subjected to additional steps, if necessary, to remove any impurities.


    Finally, the purified aldehyde is converted into the final product, 1H-Imidazole-4-carboxaldehyde,5-(1,1-dimethylethyl)-(9CI), using a variety of techniques, depending on the specific needs of the application.
    This may involve further purification, the addition of other chemicals, or the use of catalysts or other reagents to produce the desired product.


    Throughout the production process of 1H-Imidazole-4-carboxaldehyde,5-(1,1-dimethylethyl)-(9CI), care must be taken to ensure the safety of the workers involved in the production process.
    This includes the use of appropriate personal protective equipment, such as gloves and safety glasses, as well as the careful handling and storage of hazardous chemicals.
    In addition, the production process must be designed and operated in a manner that minimizes the release of any chemicals into the environment, and waste materials must be disposed of in accordance with local regulations and guidelines.


    In summary, the production of 1H-Imidazole-4-carboxaldehyde,5-(1,1-dimethylethyl)-(9CI) involves a series of carefully designed steps that are designed to produce the desired product in the most efficient and cost-effective manner possible.
    The process requires the use of specialized equipment and the expertise of trained professionals in the fields of chemistry and chemical engineering, and must be carried out in a safe and responsible manner to ensure the health and safety of all involved.


    This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only. This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed description of the concern or complaint, to service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content will be removed immediately.

    Contact Us

    The source of this page with content of products and services is from Internet, which doesn't represent ECHEMI's opinion. If you have any queries, please write to service@echemi.com. It will be replied within 5 days.

    Moreover, if you find any instances of plagiarism from the page, please send email to service@echemi.com with relevant evidence.