The Production Process of 2-(TERT-BUTYL)-4,5-DICHLORO-2,3-DIHYDROPYRIDAZIN-3-ONE

The production process of 2-(tert-butyl)-4,5-dichloro-2,3-dihydro-pyridazin-3-one, also known as TBDP, is a complex multi-step process that involves several chemical reactions and purification steps.
The process can be broken down into several main stages, including the preparation of the starting materials, the reaction step, and the purification step.

The preparation of the starting materials involves the synthesis of the precursor molecule, 2-(tert-butyl)-5-chloropyridine-4,6-dicarboxylic acid (TBDCA).
This precursor molecule is synthesized by a series of chemical reactions that involve the condensation of 2,3-dihydro-pyridine-4-carboxylic acid and 1,2-dichloro-ethylene.
The TBDCA precursor is then treated with a base, such as sodium hydroxide, to convert it to the sodium salt.

The next step in the process is the reaction step, where the TBDCA sodium salt is treated with a compound called 2,3-dichloro-5-fluoropyridine in the presence of a solvent, such as acetonitrile.
This reaction causes a series of chemical reactions to occur, leading to the formation of the final product, 2-(tert-butyl)-4,5-dichloro-2,3-dihydro-pyridazin-3-one.

The final step in the process is the purification step, where the final product is separated from any impurities that may have formed during the reaction step.
This can be done using a variety of methods, such as crystallization, chromatography, or distillation.
The purified TBDP product is then dried and packaged for shipment to customers.

The production process of TBDP is a complex and multi-step process that requires careful control of the reaction conditions and purification steps to ensure the quality of the final product.
The production of TBDP is a cost-effective process, and the use of a solvent such as acetonitrile allows for the efficient and economical production of TBDP at scale.

The synthesis of TBDP has been well-researched, and the reaction conditions and purification steps have been extensively studied.
The reaction can be carried out at room temperature, and the product can be isolated in high yield using common purification methods.
The use of acetonitrile as a solvent allows for the efficient extraction of the product from the reaction mixture, and the product can be purified using chromatography or crystallization.

In conclusion, the production of 2-(tert-butyl)-4,5-dichloro-2,3-dihydro-pyridazin-3-one is a complex process that involves several chemical reactions and purification steps.
The use of acetonitrile as a solvent allows for the efficient production of TBDP at scale, and the final product can be purified using common methods such as crystallization, chromatography, or distillation.
The production of TBDP is a cost-effective process that allows for the efficient and economical production of this important chemical intermediate.