The Production Process of (6-Chloro-2-methanesulfinyl-pyrimidin-4-yl)-ethyl-amine

The production process of (6-chloro-2-methanesulfinyl-pyrimidin-4-yl)-ethyl-amine, also known as MCC-1, is a complex process that involves several steps.
This article will provide a comprehensive overview of the production process of MCC-1 in the chemical industry, including the starting materials, reaction conditions, and purification methods.

Starting Materials

The production of MCC-1 involves several starting materials, including pyrimidine-2,4-diamine, chloroacetyl chloride, and sodium carbonate.
Pyrimidine-2,4-diamine is a precursor that is derived from the reaction between dimethyl-formamide and urea.
Chloroacetyl chloride is a chemical that is used to introduce the chlorine atom into the pyrimidine ring.
Sodium carbonate is a strong base that is used to neutralize the carboxylic acid group formed during the reaction.

Reaction Conditions

The reaction conditions for the production of MCC-1 are carefully controlled to ensure optimal yield and purity.
The reaction typically takes place in an organic solvent such as toluene or xylene, in the presence of a polar protic solvent such as water or ethanol.
The reaction is typically carried out at a temperature between 50°C and 70°C, and the reaction mixture is partially or fully decompressed to help the reaction proceed.
The exact reaction conditions may vary depending on the specific process used by the chemical manufacturer.

Purification Methods

After the reaction is complete, the resulting product mixture is typically purified using several methods.
These methods include distillation, crystallization, and chromatography.
Distillation involves heating the reaction mixture to separate the different components based on their boiling points.
Crystallization involves cooling the reaction mixture to allow the desired product to crystallize out, while chromatography involves passing the reaction mixture through a column packed with a stationary phase to separate the components based on their adsorption properties.

Other Process Variables

In addition to the starting materials, reaction conditions, and purification methods, other process variables may also be used to optimize the production process of MCC-1.
These variables include the choice of solvent, the concentration of the reactants, and the reaction time.
The specific conditions that are used will depend on the specific process used by the chemical manufacturer.

Economic Considerations

The production process of MCC-1 involves several steps, and each step must be carefully optimized to ensure optimal yield and purity.
The cost of production will depend on the specific process used, the purity of the final product, and the scale of production.
In general, the cost of production will be highest for small-scale production and will decrease as the scale of production increases.

Conclusion

The production process of MCC-1, also known as (6-chloro-2-methanesulfinyl-pyrimidin-4-yl)-ethyl-amine, is a complex process that involves several steps.
The process typically involves the use of several starting materials, carefully controlled reaction conditions, and several purification methods.
The exact process conditions will depend on the specific process used by the chemical manufacturer, and the cost of production will depend on the scale of production.
Overall, the production of MCC-1 is a challenging process that requires careful optimization of multiple variables.