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    Home > Active Ingredient News > Antitumor Therapy > The Production Process of L-Glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-, sodium salt (1:2)

    The Production Process of L-Glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-, sodium salt (1:2)

    • Last Update: 2023-04-25
    • Source: Internet
    • Author: User
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    The production process of L-glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-, sodium salt (1:2) involves several steps, including the synthesis of the starting materials, the reaction conditions, and the isolation and purification of the final product.


    The synthesis of the starting materials involves several steps, including the synthesis of 2-aminomaleic acid, which is a key intermediate in the production process.
    This can be synthesized using various methods, such as the hydrazone method, the esterification method, or the azide method.
    Once the 2-aminomaleic acid has been synthesized, it can be activated with a derivative of N-hydroxysuccinimide, followed by the addition of a benzoyl chloride.


    The reaction conditions for the production of L-glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-, sodium salt (1:2) are crucial for the success of the process.
    The reaction is typically carried out in the presence of a solvent, such as ethanol or water, at a temperature of between 50 and 80 degrees Celsius.
    The reaction can also be catalyzed by various reagents, such as triethylamine or pyridine.


    After the reaction has been completed, the product is isolated and purified using various methods, such as crystallization, chromatography, or recrystallization.
    The final product is then dried and packaged for commercial use.


    The production process of L-glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-, sodium salt (1:2) 2000 is a complex and multi-step process that requires strict control over the synthesis, reaction conditions, and purification of the final product.
    The success of the process depends on the quality and purity of the starting materials, as well as the skill and expertise of the production team.


    In conclusion, the production process of L-glutamic acid, N-[4-[2-(2-amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-, sodium salt (1:2) 2000 involves several steps, including the synthesis of the starting materials, the reaction conditions, and the isolation and purification of the final product.
    The success of the process depends on strict control over these various steps and the expertise of the production team.


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