The results show that paclitaxel combined with ultrasound can further prolong the life span of mice with brain cancer

Recently, published in the Journal of the American Cancer Research Association, scientists from northwest medicine have used a new technology to open the blood-brain barrier through implantable ultrasound, and the drug (http:// has been specifically delivered to mice's tumors Scientists also found that the brain toxicity of paclitaxel to the brain was caused by the solution needed to dissolve the drug (Cremophor) Scientists tested a solution formula for a new drug (http:// that uses albumin instead of Cremophor, proving it's not harmful to the brain Ultrasound opens the blood-brain barrier and increases the concentration of paclitaxel in the brain five times This study also showed that paclitaxel can significantly prolong the life of mice with brain tumors, while combined with ultrasound can further prolong the life of mice with brain cancer Under laboratory conditions, paclitaxel is more effective than temozolomide In vitro experiments showed that the concentration of paclitaxel required to kill the same number of tumor cells was 1400 times less than that of conventional chemotherapy for this type of cancer