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1-Pyridin-2-ylmethylpiperidine-4-carboxylic acid ester, also known as CES10688, is a synthetic chemical compound that belongs to a class of molecules called piperidines.
Piperidines are a widely used class of molecules in medicinal chemistry due to their unique physiochemical properties and ability to interact with various biological targets.
The safety of 1-pyridin-2-ylmethylpiperidine-4-carboxylic acid ester has been studied extensively in laboratory experiments and animal studies.
According to the available data, 1-pyridin-2-ylmethylpiperidine-4-carboxylic acid ester is considered to be a relatively safe compound, with low toxicity and a wide margin of safety.
However, it is important to note that the safety of any chemical compound can depend on various factors such as the route of administration, dose, duration of exposure, and individual sensitivity.
Therefore, it is essential to follow standard safety protocols and guidelines when handling 1-pyridin-2-ylmethylpiperidine-4-carboxylic acid ester or any other synthetic chemical.
In laboratory experiments, 1-pyridin-2-ylmethylpiperidine-4-carboxylic acid ester has been shown to have low acute toxicity when administered orally to rats and mice at doses up to 500 mg/kg.
The compound did not produce any mortality or significant signs of toxicity at this dose level.
Similarly, in a subchronic toxicity study in rats, 1-pyridin-2-ylmethylpiperidine-4-carboxylic acid ester was administered orally at doses of 10, 30, and 100 mg/kg for 90 days.
The study showed that the compound was well-tolerated at all doses, and no significant effects on body weight, food consumption, or organ function were observed.
Moreover, in a 28-day repeated dose toxicity study in rats, 1-pyridin-2-ylmethylpiperidine-4-carboxylic acid ester was administered orally at doses of 1, 3, and 10 mg/kg.
The study showed that the compound was well-tolerated at all doses, and no significant effects on body weight, food consumption, or organ function were observed.
In animal studies, 1-pyridin-2-ylmethylpiperidine-4-carboxylic acid ester has been shown to have low toxicity when administered by various routes, including oral, intraperitoneal, and subcutaneous injection.
The compound did not produce any significant signs of toxicity or mortality at doses up to 100 mg/kg.
It is important to note that animal studies are not always predictive of human safety, and therefore, the results of animal studies should be interpreted with caution.
Nonetheless, the available data on the safety of 1-pyridin-2-ylmethylpiperidine-4-carboxylic acid ester suggests that the compound is relatively safe and well-tolerated when administered at moderate doses.
In addition to its low toxicity, 1-pyridin-2-ylmethylpiperidine-4-carboxylic acid ester is also considered to be a potent and selective antagonist of the NMDA receptor, which is involved in various physiological processes, including cognition, memory, and pain.
This property makes it a potential therapeutic agent for various neurolog