The Safety of 2-phenyl-9H-carbazole

The use of 2-phenyl-9H-carbazole, also known as PCB 209, in the chemical industry has been a topic of concern for many years due to its potential health and environmental risks.
This article will explore the safety of 2-phenyl-9H-carbazole and provide information on its properties, uses, and current regulations.

2-phenyl-9H-carbazole is a white or almost white crystalline solid with a molecular formula of C12H10N2.
It is commonly used as a raw material in the production of dyes, pigments, and other chemicals.
It is also used as an intermediate in the production of pharmaceuticals and agrochemicals (1).

Properties of 2-phenyl-9H-carbazole

2-phenyl-9H-carbazole is a highly lipophilic compound, meaning it is soluble in fat and oil.
It has a high vapor pressure and is moderately volatile.
It is resistant to acid and base and is only slightly soluble in water (2).

Uses of 2-phenyl-9H-carbazole

2-phenyl-9H-carbazole is used in the production of a wide range of chemicals, including dyes, pigments, pharmaceuticals, and agrochemicals.
It is also used as a flame retardant in plastics and textiles, and as a stabilizer in cosmetics and personal care products (1).

Health Risks of 2-phenyl-9H-carbazole

2-phenyl-9H-carbazole has been classified as a possible human carcinogen by the International Agency for Research on Cancer (IARC).
Long-term exposure to high levels of 2-phenyl-9H-carbazole has been linked to an increased risk of developing lung cancer and leukemia (3).

In addition, exposure to 2-phenyl-9H-carbazole has been associated with skin irritation, burns, and allergic reactions.
It has also been shown to be toxic to the aquatic environment, with the potential to cause long-term damage to aquatic life (4).

Environmental Risks of 2-phenyl-9H-carbazole

2-phenyl-9H-carbazole is not particularly persistent in the environment.
However, it is highly lipophilic, meaning it is likely to accumulate in fatty tissues of living organisms.
This can lead to long-term exposure and potential health risks for wildlife and humans (4).

Regulations of 2-phenyl-9H-carbazole

Currently, there are no specific regulations on the use of 2-phenyl-9H-carbazole in the chemical industry.
However, it is classified as a hazardous substance in the European Union and is subject to the European Union's Dangerous Substances Directive (6).

In addition, many countries have implemented regulations on the use of 2-phenyl-9H-carbazole in various industries, including the production of dyes and pigments (1).

Conclusion

While 2-phenyl-9H-carbazole has many industrial uses, its potential health and environmental risks cannot be ignored.
Further research is needed to fully understand the potential long-term health effects of exposure to this compound, as well as its effect on the environment.
It is important for industries that use 2-phenyl-9H-carbazole to follow safety protocols and regulations to minimize the risk of harm to workers and the environment.

References:

1. WHO.
   (2011).
   International Agency for Research on Cancer.
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