-
Categories
-
Pharmaceutical Intermediates
-
Active Pharmaceutical Ingredients
-
Food Additives
- Industrial Coatings
- Agrochemicals
- Dyes and Pigments
- Surfactant
- Flavors and Fragrances
- Chemical Reagents
- Catalyst and Auxiliary
- Natural Products
- Inorganic Chemistry
-
Organic Chemistry
-
Biochemical Engineering
- Analytical Chemistry
- Cosmetic Ingredient
-
Pharmaceutical Intermediates
Promotion
ECHEMI Mall
Wholesale
Weekly Price
Exhibition
News
-
Trade Service
To show how the new coronavirus has changed since the outbreak, a team led by Morgan Rowland of the Walter Reed Army Research Institute (WRAIR) compared the virus genome sequences from samples from 84 countries and combed through the variations.
analysis showed limited diversity across the neo-coronavirus genome: only 11 bits showed polymorphism greater than 5%.
so far, the evolution of the new coronavirus genome has been primarily a random process rather than an adaptive choice.
"As other studies have noted, we have noticed a rapid increase in the frequency of D614G mutations in the new coronavirus pyrethroid protein since the outbreak, but we cannot link this mutation to specific adaptability," Roland said.
when the virus replicates and spreads in a population, we see mutations that can be fixed at random very quickly.
" Roland stressed that linking genotypes to esotypes is complex and more research is needed to fully understand the functional consequences of D614G mutations in the new coronavirus.
addition, given the limited genetic variation of the new coronavirus, promising candidate vaccines may have the same effect on all new coronavirus strains currently in transmission.
" efforts to develop vaccines for AIDS, influenza and dengue face the challenge of diversity of these viruses, but analysis of samples from around the world shows that the diversity of new coronavirus is lower than that of these viruses.
, we can be cautiously optimistic that virus diversity will not be an obstacle to the development of a broad range of protective vaccines against new coronavirus infections.
" it is reported that WRAIR is also currently developing a vaccine, its candidate vaccine based on the prickly ferrin nanoparticle platform, is expected to be conducted in humans by 2021.
the vaccine with WRAIR's patented adjunction, the Army Lipid Formula, to further enhance the immune response.
.