The small mammal adaptive evolution and management discipline group has made new progress in the study of the composition and function of the intestinal flora of plateau pikas in response to swainsonine compounds

The plateau pika ( Ochotona curzoniae ) is a small herbivorous mammal unique to the Qinghai-Tibet Plateau.

In order to solve the above problems, the Small Mammal Adaptive Evolution and Management Discipline Group of Northwest Plateau Institute of Biology, Chinese Academy of Sciences will raise plateau pikas caught in the wild indoors for long-term (20 weeks) and short-term (2 weeks) breeding, and add them to the feed SW conducted a feeding experiment to determine the composition of the plateau pika fecal flora and the concentration of short-chain fatty acids (SCFA)

The results of such studies related to The plant secondary compound swainsonine reshapes gut microbiota in plateau pikas (Ochotona curzoniae) and Enterotypes of the gut microbial community and their response to plant secondary compounds in plateau pikas was published separately in Applied Microbiology and Biotechnology (2 Zone) and Microorganisms (Zone 2)

The research was funded by the National Natural Science Foundation of China (31670394), the major special project of Qinghai Province, "Conservation and Utilization of Representative Animal Gene Resources in the Source of Three Rivers" (2021-ZJ-Y01), and the "Western Light-Joint Scholars" project

Link to the paper: https://doi.

Figure 1 The diversity and structure of the intestinal flora of the plateau pika

Figure 2 Co-occurrence network diagram of core bacteria

Figure 3 The response of plateau pika intestinal type and flora diversity to dietary intervention