The study found 20 metabolic abnormalities in CFS patients.

In the mid-1980s, the medical profession put forward the concept of "chronic comprehensive fatigue".
Because the disease causes people to appear for unknown reasons of severe systemic burnout, accompanied by low fever, headache, muscle pain, depression, inattment and other mental symptoms, sometimes swollen lymph nodes and affect normal life, really make patients crazy.
2.5 million people in the U.S. are thought to have CFS, and while all ages and genders are affected, women between the ages of 35 and 50 are the most vulnerable.
symptoms are chronic severe fatigue that lasts for six months, along with other side effects such as muscle pain, sleep headaches, and memory problems.
there is currently no effective treatment.
Researchers at the University of California, San Diego School of Medicine used a variety of techniques to identify and evaluate target metabolites in the plasma and found specific chemical characteristics and unexpected underlying biological principles associated with this debilitating disease: it is similar to "state of state" and other symptoms of metabolic decline, such as calorie restriction, stagnant parenting, and hibernation.
dauer is a German word that means long, persistent presence.
is a retardation in the development of invertebrates caused by harsh environments.
the study was published August 29 in PNAS.
. Robert K. Naviaux of the Center for Mitochondrial and Metabolic Diseases at the University of California, San Diego School of Medicine, said, "CFS is a very challenging disease.
it affects multiple systems in the body.
variety of symptoms and are the same as other common diseases.
there are currently no diagnostic laboratory tests.
may have spent a lot of time and money before getting an accurate diagnosis.
" Naviaux and colleagues studied 84 subjects: 45 men and women who met CFS diagnostic criteria, and 39 as a control group.
researchers targeted 612 metabolites from 63 biochemical path path pathps in the plasma.
found that CFS patients had 20 metabolic abnormalities.
8% of the tested diagnosed metabolites decreased, which was consistent with metabolic slowdown symptoms, with more than 90% accuracy.
despite the heterogeneity of CFS and the variety of factors that cause the disease, our findings suggest that these patients have the same cellular metabolic response.
interestingly, this situation is chemically similar to the 'continuous state' of some organisms, where environmental stress causes metabolic slowdowns so that organisms can survive in harsh conditions without causing cell death.
in CFS, this metabolic slowdown can lead to long-term pain and reduced function.
a large number of target populations in different regions are needed to confirm the versatility and specificity of the findings.
But the findings suggest that CFS has objectively identifiable chemical properties that directly provide small molecule information to target metabolites, both male and female, and can provide practical therapeutic information.
only 25% of these metabolic abnormalities need to be used for CFS diagnosis.
the remaining 75 percent of metabolic abnormalities vary from person to person, Naviaux believes this could be used for personalized treatment.
opens the way for understanding the biology of CFS, and more importantly for patients to develop new treatments.
source: Source: Supplied