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    Home > Active Ingredient News > Drugs Articles > The study found that: mung bean protein isolate can reduce the dietary weight gain caused by high fat diet

    The study found that: mung bean protein isolate can reduce the dietary weight gain caused by high fat diet

    • Last Update: 2018-08-22
    • Source: Internet
    • Author: User
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    Published in the Journal of biochemical and biophysical research letters, a new animal study found that mung bean protein isolate (glucida) can reduce the dietary weight gain, fat accumulation and fatty degeneration of liver caused by high-fat diet (fatty liver mainly accumulated) The researchers randomly assigned a high-fat diet or a high-fat diet with mung bean separated eggs to the regular mice for 4 weeks At the same time, sterile mice were randomly divided into high-fat diet or high-fat diet containing mung bean protein, lasting for 4 weeks During the course of the study, weight was measured weekly and fecal samples were collected The mice were then euthanized and their liver, cecum, epididymis, perirenal and subcutaneous adipose tissue collected and weighed The researchers studied both conventionally bred and sterile mice to analyze (http://www.chemdrug.com/sell/76/) and compare changes in gut microbes The results showed that the weight gain of mice fed a high-fat diet containing mung bean protein was less at the end of the second week, while those fed / not fed mung bean protein did not increase over time The weight of epididymis, perirenal and subcutaneous adipose tissue was also lower in the mungbean group, although there was no significant difference in cecal weight between the different groups In addition, the weight of the liver in the mung bean protein group was also lower, the level of triglyceride in the liver was significantly reduced, and the vacuolation of the cytoplasm was also reduced, which indicated that the steatosis was reduced As mentioned above, sterile mice were used to determine the effect of intestinal microflora on beneficial metabolism The results showed that the intestinal flora of sterile mice was significantly affected, because there was no significant difference in body and tissue weight between the high-fat diet and the high-fat diet containing mung bean protein group, and there was no reduction in liver steatosis Rats fed mungbean protein also had higher levels of gut mediated glucagon like peptide-1 (GLP-1) The results showed that GLP-1 could increase cecal bile acid capacity and secondary bile acid level This is not the case in sterile mice The anti obesity effect was eliminated in the aseptic mice fed with mung bean protein isolate, which indicated that the beneficial effect of mung bean protein isolate depended on the existence of intestinal microorganisms.
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