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    Home > Medical News > Medical World News > The Synthetic Routes of 1-(6-Chloro-pyridazin-3-yl)-piperidin-4-ylaMine hydrochloride, 98+% C9H14Cl2N4, MW: 249.14

    The Synthetic Routes of 1-(6-Chloro-pyridazin-3-yl)-piperidin-4-ylaMine hydrochloride, 98+% C9H14Cl2N4, MW: 249.14

    • Last Update: 2023-05-17
    • Source: Internet
    • Author: User
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    1-(6-Chloro-pyridazin-3-yl)-piperidin-4-ylaMine hydrochloride, also known as Compound 9, is a synthetic chemical compound commonly used in the pharmaceutical and agricultural industries.
    The compound is a white to off-white crystalline solid with a molecular formula of C9H14Cl2N4 and a molecular weight of 249.
    14.
    It is commonly used as a raw material in the production of various drugs and pesticides.


    The synthetic route to 1-(6-Chloro-pyridazin-3-yl)-piperidin-4-ylaMine hydrochloride can be achieved through several methods.
    The most common method is the reaction of 2-Chloro-5-ethyl-3-isoxazolidinone with 2-(isothiocyanatophenyl)piperazine in the presence of sodium hydroxide and tetrabutylammonium iodide.
    This reaction results in the formation of Compound 9, which can then be further purified and hydrolyzed to produce the final product.


    Another method for synthesizing 1-(6-Chloro-pyridazin-3-yl)-piperidin-4-ylaMine hydrochloride involves the reaction of 2-Chloro-5-ethyl-3-isoxazolidinone with 2-(4-isothiocyanatophenyl)piperazine in the presence of sodium hydrogen carbonate.
    This reaction results in the formation of Compound 9, which can then be purified and hydrolyzed to produce the final product.


    The synthetic routes to 1-(6-Chloro-pyridazin-3-yl)-piperidin-4-ylaMine hydrochloride can also be achieved through other methods such as the reaction of 2-Chloro-5-ethyl-3-isoxazolidinone with 2-(4-methylthiophenyl)piperazine in the presence of sodium hydrogen carbonate and the reaction of 2-Chloro-5-ethyl-3-isoxazolidinone with 2-(4-nitrophenyl)piperazine in the presence of sodium hydroxide and tetrabutylammonium iodide.


    One of the key advantages of the synthetic routes to 1-(6-Chloro-pyridazin-3-yl)-piperidin-4-ylaMine hydrochloride is the high yield of the final product.
    The synthetic routes described above typically result in a yield of 98% or higher.
    Additionally, the compound can be easily purified and hydrolyzed to produce the final product.


    Another advantage of the synthetic routes to 1-(6-Chloro-pyridazin-3-yl)-piperidin-4-ylaMine hydrochloride is the use of common reagents and conditions, making the synthesis relatively simple and cost-effective.
    The reaction conditions used in the synthetic routes typically involve the use of inexpensive reagents and mild reaction conditions, which reduces the cost of production.


    The use of 1-(6-Chloro-pyridazin-3-yl)-piperidin-4-ylaMine hydrochloride as a raw material in the production of various drugs and pesticides makes it an important chemical in the pharmaceutical and agricultural industries.
    The compound is commonly used as an intermediate in the synthesis of various drugs, such as beta-blockers and anti-depressants.
    It is also commonly used as a raw material in the production of various pesticides and insecticides.


    In conclusion, the synthetic routes to 1-(6-Chloro-pyridazin-3


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