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    Home > Medical News > Medical Science News > The Synthetic Routes of 2-Bromo-9,10-diphenylanthracene

    The Synthetic Routes of 2-Bromo-9,10-diphenylanthracene

    • Last Update: 2023-05-15
    • Source: Internet
    • Author: User
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    2-Bromo-9,10-diphenylanthracene is an important intermediate in the synthesis of a variety of organic compounds, and it has been widely used in the chemical industry.
    The synthesis of 2-bromo-9,10-diphenylanthracene can be accomplished through several synthetic routes, which can be broadly classified into two categories: synthetic routes using classical organic synthesis methods and synthetic routes using modern organic synthesis methods.


    Classical Organic Synthesis Methods


    Classical organic synthesis methods involve the use of traditional synthetic techniques, such as condensation reactions, substitution reactions, and reductions.
    One of the most commonly used classical synthetic routes to 2-bromo-9,10-diphenylanthracene involves the reaction of 2-chloro-9,10-diphenylanthracene with sodium hydroxide in aqueous solution.
    The reaction involves the dechlorination of 2-chloro-9,10-diphenylanthracene to form 2-bromo-9,10-diphenylanthracene, which is then extracted and purified to yield the desired product.
    This route is reported to have a yield of about 50%.


    Another classical synthetic route to 2-bromo-9,10-diphenylanthracene involves the reaction of 1,2-diphenylanthracene with chloroform in the presence of a Lewis acid catalyst, such as aluminum chloride.
    The reaction involves the halogenation of 1,2-diphenylanthracene to form 2-chloro-9,10-diphenylanthracene, which is then hydrolyzed to form 2-bromo-9,10-diphenylanthracene.
    This route is reported to have a yield of about 60%.


    Modern Organic Synthesis Methods


    Modern organic synthesis methods involve the use of modern synthetic techniques, such as metal-catalyzed reactions, organometallic reactions, and asymmetric synthesis.
    One of the most commonly used modern synthetic routes to 2-bromo-9,10-diphenylanthracene involves the reaction of 1,2-diphenylanthracene with bromine in the presence of a metal catalyst, such as tin(II) chloride.
    The reaction involves the substitution of bromine for chlorine in 1,2-diphenylanthracene to form 2-bromo-9,10-diphenylanthracene, which is then purified to yield the desired product.
    This route is reported to have a yield of about 90%.


    Another modern synthetic route to 2-bromo-9,10-diphenylanthracene involves the reaction of 2-chloro-9,10-diphenylanthracene with bromine in the presence of a metal catalyst, such as copper(II) bromide.
    The reaction involves the substitution of bromine for chlorine in 2-chloro-9,10-diphenylanthracene to form 2-bromo-9,10-diphenylanthracene, which is then purified to yield the desired product.
    This route is reported to have a yield of about 80%.


    Conclusion


    2-Bromo-9,10-diphenylanthracene is an important intermediate in the synthesis of a variety of organic compounds, and there are several synthetic routes available for its synthesis, including classical organic synthesis methods and modern organic synthesis methods.
    Classical organic synthesis methods involve the use of traditional synthetic techniques, such as condensation reactions and substitution reactions, while modern organic synthesis methods involve the use of modern synthetic techniques, such as metal-catal


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