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    Home > Medical News > Medical World News > The Synthetic Routes of 3,6-Dichloro-4-(4-pyridinyl)pyridazine

    The Synthetic Routes of 3,6-Dichloro-4-(4-pyridinyl)pyridazine

    • Last Update: 2023-05-15
    • Source: Internet
    • Author: User
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    3,6-Dichloro-4-(4-pyridinyl)pyridazine is a synthetic compound that has various applications in the chemical industry.
    It is commonly used as a building block for the synthesis of other chemicals and pharmaceuticals.
    The synthetic routes for this compound can be broadly classified into two categories: classical synthesis and modern synthesis.


    Classical synthesis involves the use of traditional chemical methods and reactions to synthesize a compound.
    This method is often less expensive and requires less technical expertise compared to modern synthesis.
    One of the classical synthetic routes for 3,6-dichloro-4-(4-pyridinyl)pyridazine involves the reaction of 4-chloro-3,6-dibromopyridazine with 4-pyridylboronic acid in the presence of a base such as sodium hydroxide.
    The product is then purified by recrystallization or chromatography.


    Modern synthesis, on the other hand, involves the use of more advanced and sophisticated chemical methods and techniques to synthesize a compound.
    This method often requires specialized equipment and technical expertise, but it is generally more efficient and produces higher quality products.
    One of the modern synthetic routes for 3,6-dichloro-4-(4-pyridinyl)pyridazine involves the reaction of 4-chloro-3,6-dibromopyridazine with 4-pyridylboronic acid in the presence of a catalyst such as tetrakis(triphenylphosphine)palladium(0) and a solvent such as toluene.
    The product is then purified by chromatography or other appropriate methods.


    Another modern synthetic route for 3,6-dichloro-4-(4-pyridinyl)pyridazine involves the reaction of 4-iodo-3,6-dibromopyridazine with 4-pyridylboronic acid in the presence of a catalyst such as tris(dibenzylideneacetone)dipalladium(0) and a solvent such as toluene.
    The product is then purified by chromatography or other appropriate methods.


    No matter what the synthetic route, the final product must be purified and characterized to ensure its quality and identity.
    The purification process may involve recrystallization, chromatography, or other appropriate methods.
    The characterization process may involve various techniques such as spectroscopy, spectrometry, or other appropriate methods.


    The synthetic routes for 3,6-dichloro-4-(4-pyridinyl)pyridazine vary depending on the specific application and the desired product properties.
    The choice of synthetic route will depend on various factors such as the cost, efficiency, and availability of the starting materials and the desired product properties.
    The use of modern synthesis methods is often more efficient and produces higher quality products, but it may also be more expensive and require specialized equipment.


    In conclusion, 3,6-dichloro-4-(4-pyridinyl)pyridazine is an important synthetic compound with various applications in the chemical industry.
    The synthetic routes for this compound can be broadly classified into classical synthesis and modern synthesis.
    The choice of synthetic route will depend on various factors such as the cost, efficiency, and availability of the starting materials and the desired product properties.
    The final product must be purified and characterized to ensure its quality and identity.


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