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4-(6-Chloro-pyridazine-3-yl)-piperazine-1-carboxylic acid tert-butyl ester is an organic compound widely used in various industries, including the chemical, pharmaceutical, and agrochemical industries.
The compound is known for its unique properties and versatile applications.
In this article, we will discuss the synthetic routes of 4-(6-Chloro-pyridazine-3-yl)-piperazine-1-carboxylic acid tert-butyl ester.
Synthetic routes are the methods used to synthesize a particular compound.
There are many synthetic routes for 4-(6-Chloro-pyridazine-3-yl)-piperazine-1-carboxylic acid tert-butyl ester, and each route has its advantages and disadvantages.
In this article, we will discuss some of the commonly used synthetic routes for the preparation of 4-(6-Chloro-pyridazine-3-yl)-piperazine-1-carboxylic acid tert-butyl ester.
One of the commonly used synthetic routes for the preparation of 4-(6-Chloro-pyridazine-3-yl)-piperazine-1-carboxylic acid tert-butyl ester is the Ritter reaction.
The Ritter reaction is a reaction of an amide with an aldehyde in the presence of an acid catalyst.
The reaction is known for its ease of operation, high yield, and mild conditions, making it a popular choice for the synthesis of 4-(6-Chloro-pyridazine-3-yl)-piperazine-1-carboxylic acid tert-butyl ester.
Another commonly used synthetic route for the preparation of 4-(6-Chloro-pyridazine-3-yl)-piperazine-1-carboxylic acid tert-butyl ester is the Grignard reaction.
The Grignard reaction is a reaction of an alkyl halide with magnesium metal in ether or other polar protic solvents.
The reaction is known for its ease of operation, and the ability to prepare a wide range of compounds, making it a popular choice for the synthesis of 4-(6-Chloro-pyridazine-3-yl)-piperazine-1-carboxylic acid tert-butyl ester.
A third synthetic route for the preparation of 4-(6-Chloro-pyridazine-3-yl)-piperazine-1-carboxylic acid tert-butyl ester is the Williamson reaction.
The Williamson reaction is a reaction of an alkyl halide with a metal carbonate in the presence of a base.
The reaction is known for its ease of operation, and the ability to prepare a wide range of compounds, making it a popular choice for the synthesis of 4-(6-Chloro-pyridazine-3-yl)-piperazine-1-carboxylic acid tert-butyl ester.
A fourth synthetic route for the preparation of 4-(6-Chloro-pyridazine-3-yl)-piperazine-1-carboxylic acid tert-butyl ester is the Stille reaction.
The Stille reaction is a reaction of an alkyl halide with a metal carbene in the presence of a Lewis acid catalyst.
The reaction is known for its ease of operation, and the ability to prepare a wide range of compounds, making it a popular choice for the synthesis of 4-(6-Chloro-pyridazine-3-yl)-piperazine-1-carboxylic acid tert-butyl ester.
In conclusion, there are several synthetic routes for the preparation of 4-(6-Chloro-pyridazine-3-yl)-piperazine-1-carboxylic acid