 Home > Medical News > Medical Research Articles > The Synthetic Routes of 5-Azaspiro[2.4]heptane, 6-[5-[7-[2-(1R,3S,4S)-2-azabicyclo[2.2.1]hept-3-yl-1H-benzimidazol-6-yl]-9,9-difluoro-9H-fluoren-2-yl]-1H-imidazol-2-yl]-, hydrochloride (1:4), (6S)-

The Synthetic Routes of 5-Azaspiro[2.4]heptane, 6-[5-[7-[2-(1R,3S,4S)-2-azabicyclo[2.2.1]hept-3-yl-1H-benzimidazol-6-yl]-9,9-difluoro-9H-fluoren-2-yl]-1H-imidazol-2-yl]-, hydrochloride (1:4), (6S)-

 Last Update: 2023-05-16
 Source: Internet
 Author: User

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Introduction:

5-Azaspiro[2.
4]heptane, 6-[5-[7-[2-(1R,3S,4S)-2-azabicyclo[2.
2.
1]hept-3-yl-1H-benzimidazol-6-yl]-9,9-difluoro-9H-fluoren-2-yl]-1H-imidazol-2-yl]-, hydrochloride (1:4), (6S)- is a synthetic compound that has a unique structure and possesses potential pharmacological properties.
This compound is of considerable interest to researchers due to its ability to interact with various cellular targets, making it a potential therapeutic agent for a range of diseases.
In this article, we will discuss the synthetic routes of 5-Azaspiro[2.
4]heptane, 6-[5-[7-[2-(1R,3S,4S)-2-azabicyclo[2.
2.
1]hept-3-yl-1H-benzimidazol-6-yl]-9,9-difluoro-9H-fluoren-2-yl]-1H-imidazol-2-yl]-, hydrochloride (1:4), (6S)-.

Background:

5-Azaspiro[2.
4]heptane, 6-[5-[7-[2-(1R,3S,4S)-2-azabicyclo[2.
2.
1]hept-3-yl-1H-benzimidazol-6-yl]-9,9-difluoro-9H-fluoren-2-yl]-1H-imidazol-2-yl]-, hydrochloride (1:4), (6S)- is a synthetic compound that is known for its unique chemical structure.
It is a member of a class of compounds called benzimidazoles, which are known for their ability to interact with various cellular targets, making them potential therapeutic agents for a range of diseases.

Methods:

There are several synthetic routes to 5-Azaspiro[2.
4]heptane, 6-[5-[7-[2-(1R,3S,4S)-2-azabicyclo[2.
2.
1]hept-3-yl-1H-benzimidazol-6-yl]-9,9-difluoro-9H-fluoren-2-yl]-1H-imidazol-2-yl]-, hydrochloride (1:4), (6S)-.
Some of the commonly used methods include:

Synthesis via a Pd(II)-catalyzed reaction: This involves the reaction of a suitably substituted amine with a suitably substituted aldehyde in the presence of a Pd(II) catalyst.
Synthesis via a Suzuki coupling reaction: This involves the reaction of a boronic acid derivative with a suitably substituted boronic acid derivative in the presence of a Suzuki coupling reagent.
Synthesis via a Stille coupling reaction: This involves the reaction of a suitably substituted aldehyde with a suitably substituted tert-butyldimethylsilyl iodide in the presence of a palladium catalyst.

Results:

The synthetic routes to 5-Azaspiro[2.
4]heptane, 6-[5-[7-[2-(1R,3S,4S)-2-azabicyclo[2.
2.
1]hept-3-yl-1H-benzimidazol-6-yl]-9,9-difluoro-9H-flu

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