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2-(Morpholin-4-ylamino)pyridine-5-boronic acid pinacol ester is an important intermediate chemical used in the production of various downstream products in the chemical industry.
As an upstream product, it is derived from the synthesis of various starting materials, including boronic acids and morpholine.
Downstream Products
2-(Morpholin-4-ylamino)pyridine-5-boronic acid pinacol ester is a versatile intermediate chemical that can be converted into a variety of downstream products through different chemical reactions.
Some of the key downstream products include:
- Pesticides: 2-(Morpholin-4-ylamino)pyridine-5-boronic acid pinacol ester can be converted into a variety of pesticides, including insecticides, fungicides, and herbicides.
These products are widely used in agriculture to protect crops from pests and diseases. - Pharmaceuticals: The boronic acid group present in 2-(Morpholin-4-ylamino)pyridine-5-boronic acid pinacol ester can be converted into various boronic acid-containing drugs, such as antibiotics, anticancer drugs, and anti-inflammatory drugs.
- Personal Care Products: 2-(Morpholin-4-ylamino)pyridine-5-boronic acid pinacol ester can be used in the production of various personal care products, including shampoos, soaps, and lotions.
- Agrochemicals: 2-(Morpholin-4-ylamino)pyridine-5-boronic acid pinacol ester can be converted into a variety of agrochemicals, including plant growth regulators, plant protections, and crop nutrients.
Upstream Products
2-(Morpholin-4-ylamino)pyridine-5-boronic acid pinacol ester is an upstream product that is derived from the synthesis of various starting materials, including boronic acids and morpholine.
The production process typically involves the following steps:
- Synthesis of boronic acid: Boronic acid is typically synthesized from boric acid and an alkali metal salt, such as sodium hydroxide.
The reaction involves the neutralization of the boric acid with the salt to produce the boronic acid. - Synthesis of morpholine: Morpholine is typically synthesized from ammonia and acetaldehyde.
The reaction involves the hydrolysis of the imine formed between ammonia and acetaldehyde to produce morpholine. - Synthesis of 2-(Morpholin-4-ylamino)pyridine-5-boronic acid pinacol ester: The synthesis of 2-(Morpholin-4-ylamino)pyridine-5-boronic acid pinacol ester involves the condensation of 2-(morpholin-4-ylamino)pyridine with pinacol boronate in the presence of a solvent, such as dichloromethane or toluene.
Manufacturing Process
The manufacturing process for 2-(Morpholin-4-ylamino)pyridine-5-boronic acid pinacol ester typically involves the following steps:
- Synthesis of boronic acid: The synthesis of boronic acid is typically carried out in a reaction vessel equipped with a stirring system, a temperature control system, and a condenser.
Sodium hydroxide is added to boric acid, and the reaction mixture is agitated to ensure complete neutralization. - Synthesis of morpholine: The synthesis of morpholine is typically carried out in a reaction vessel equipped with a stirring system and a temperature control system.
Ammonia and acetaldehyde are added to the