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    Home > Medical News > Medical World News > The Upstream and Downstream products of 4-Bromopyridazine

    The Upstream and Downstream products of 4-Bromopyridazine

    • Last Update: 2023-05-18
    • Source: Internet
    • Author: User
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    Introduction


    In the chemical industry, one of the most important aspects is the production of various chemical compounds.
    One such compound is 4-Bromopyridazine, which is used in a wide range of applications in industries such as pharmaceuticals, agrochemicals, and textiles.
    In this article, we will be discussing the upstream and downstream products of 4-Bromopyridazine, and the processes involved in their production.


    Upstream Products


    The upstream products of 4-Bromopyridazine refer to the raw materials and intermediates used in its production.
    One of the most important upstream products is 2-pyridinecarboxaldehyde, which is used as a starting material in the synthesis of 4-Bromopyridazine.
    This compound is synthesized by a multi-step process that involves the reduction of 2-pyridinecarboxylic acid with lithium aluminum hydride (LiAlH4) in the presence of a solvent such as ether or THF.


    Another important upstream product is N-bromosuccinimide (NBS), which is used as a reagent in the synthesis of 4-Bromopyridazine.
    NBS is synthesized by a simple reaction between chlorosuccinimide (ClS(CH2)3) and bromine (Br2) in the presence of a solvent such as carbon tetrachloride (CCl4).
    The reaction between these two compounds results in the formation of NBS, which can then be used as a reagent in the synthesis of 4-Bromopyridazine.


    Downstream Products


    The downstream products of 4-Bromopyridazine refer to the various chemical compounds that are derived from it.
    One of the most important downstream products is 4-Amino-3-bromopyridine, which is used as an intermediate in the production of various pharmaceuticals, agrochemicals, and textiles.
    This compound is synthesized by a simple reaction between 4-Bromopyridazine and ammonia (NH3) in the presence of a solvent such as pyridine.
    The reaction between these two compounds results in the formation of 4-Amino-3-bromopyridine, which can then be used as an intermediate in the production of various chemicals.


    Another important downstream product of 4-Bromopyridazine is 2-Bromopyridine-5-carboxylic acid, which is used as a starting material in the production of various agrochemicals.
    This compound is synthesized by a multi-step process that involves the oxidation of 4-Bromopyridazine with potassium permanganate (KMnO4) in the presence of a solvent such as water, followed by the decarboxylation of the resulting compound.


    Processes Involved in Production


    The production of 4-Bromopyridazine and its downstream products involves a series of chemical reactions and processes.
    The following are the key steps involved in the production of 4-Bromopyridazine and its downstream products:


    1. Synthesis of 2-Pyridinecarboxaldehyde: This involves the reduction of 2-pyridinecarboxylic acid with LiAlH4 in the presence of a solvent such as ether or THF.
    2. Synthesis of N-Bromosuccinimide (NBS): This involves the reaction between chlorosuccinimide (ClS(CH

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