The Upstream and Downstream products of 4-Fluoro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid

4-Fluoro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid is a synthetic organic compound that is widely used in the chemical industry.
It is a key intermediate in the production of several important chemicals and pharmaceuticals.
In this article, we will discuss the upstream and downstream products of 4-Fluoro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid.

Upstream Products
The production of 4-Fluoro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid involves several upstream processes.
One of the most important upstream processes is the production of 4-Fluoro-7H-pyrrolo[2,3-d]pyrimidine-5-carboxylic acid.
This compound is produced by reacting 2,6-lutidine with acrylic acid in the presence of a strong acid catalyst, such as sulfuric acid.
The reaction produces a mixture of the desired 4-Fluoro-7H-pyrrolo[2,3-d]pyrimidine-5-carboxylic acid and other byproducts, which must be purified to obtain the pure compound.

Another upstream product is 4-Fluoro-7H-pyrrolo[2,3-d]pyrimidine-2,5-diones, which is produced by the reduction of 4-Fluoro-7H-pyrrolo[2,3-d]pyrimidine-5-carboxylic acid with a reducing agent such as lithium aluminum hydride.
The reduction reaction produces a mixture of the desired 4-Fluoro-7H-pyrrolo[2,3-d]pyrimidine-2,5-diones and other byproducts, which must be purified to obtain the pure compound.

Downstream Products
The most common downstream product of 4-Fluoro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid is 4-fluoro-7H-pyrrolo[2,3-d]pyrimidine-2-one, which is produced by the reduction of 4-Fluoro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid with a reducing agent such as hydrogen in the presence of a heavy metal catalyst, such as palladium on barium oxide.
The reduction reaction produces a mixture of the desired 4-Fluoro-7H-pyrrolo[2,3-d]pyrimidine-2-one and other byproducts, which must be purified to obtain the pure compound.

Another downstream product of 4-Fluoro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid is 4-Fluoro-7H-pyrrolo[2,3-d]pyrimidine-5-one, which is produced by the oxidation of 4-Fluoro-7H-pyrrolo[2,3-d]pyrimidine-2-one with a strong oxidizing agent such as potassium permanganate.
The oxidation reaction produces a mixture of the desired 4-Fluoro-7H-pyrrolo[2,3-d]pyrimidine-5-one and other byproducts, which must be purified to obtain the pure compound.

4-Fluoro-7H-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid is also used as an intermediate in the production of