The Upstream and Downstream products of 7-BROMO-ISOQUINOLIN-1-YLAMINE

7-BROMO-ISOQUINOLIN-1-YLAMINE: An Important Intermediate in the Chemical Industry

7-Bromo-isoquinolin-1-ylamine, also known as 7-bromo-IQ, is an important intermediate in the chemical industry.
It is used in the production of various chemicals, pharmaceuticals, and agrochemicals.
The upstream and downstream products of 7-bromo-isoquinolin-1-ylamine will be discussed in this article.

Upstream Products of 7-Bromo-ISOQUINOLIN-1-YLAMINE

The upstream products of 7-bromo-isoquinolin-1-ylamine are the raw materials required for its production.
The main raw materials used in the production of 7-bromo-isoquinolin-1-ylamine are bromine and isoquinolin-1-one.
Bromine is obtained from the natural element bromine, which is found in seawater and brine pools.
It is one of the most readily available raw materials for the production of 7-bromo-isoquinolin-1-ylamine.

Isoquinolin-1-one, on the other hand, is derived from the reaction of phenylalanine with hydrogen cyanide.
It is a crucial raw material in the production of 7-bromo-isoquinolin-1-ylamine.

Downstream Products of 7-BROMO-ISOQUINOLIN-1-YLAMINE

The downstream products of 7-bromo-isoquinolin-1-ylamine are the chemicals, pharmaceuticals, and agrochemicals that are produced using 7-bromo-isoquinolin-1-ylamine as an intermediate.
The following are some of the most common downstream products of 7-bromo-isoquinolin-1-ylamine:

1. Pharmaceuticals:
   7-bromo-isoquinolin-1-ylamine is used in the production of various pharmaceuticals, including antihistamines, antipsychotics, and antidepressants.
   It is also used in the production of local anesthetics and muscle relaxants.
   
2. Agrochemicals:
   7-bromo-isoquinolin-1-ylamine is used in the production of herbicides, insecticides, and fungicides.
   It is used as an intermediate in the production of various agrochemicals, such as bromoxynil, which is used to control weeds in crops.
   
3. Intermediates:
   7-bromo-isoquinolin-1-ylamine is also used as an intermediate in the production of other chemicals, such as dyes, fragrances, and pharmaceutical intermediates.
   

Production of 7-BROMO-ISOQUINOLIN-1-YLAMINE

The production of 7-bromo-isoquinolin-1-ylamine involves several steps, including:

1. Bromination of Isoquinolin-1-one:
   The bromination of isoquinolin-1-one is the first step in the production of 7-bromo-isoquinolin-1-ylamine.
   It is carried out using bromine and a solvent, such as acetonitrile or DMF.
   The reaction is typically carried out at a temperature of 50-60°C and a bromine-to-isoquinolin-1-one ratio of 2:1.
   
2. Reduction of 7-Bromo-Isoquinolin-1-one:
   The next step in the production of 7-bromo-isoquinolin-1-ylamine