The Upstream and Downstream products of N-(2-Chloro-4-pyrimidinyl)-2,3-dimethyl-2H-indazol-6-amine

N-(2-Chloro-4-pyrimidinyl)-2,3-dimethyl-2H-indazol-6-amine, also known as Meta (CAS No: 1031684-12-4), is a chemical compound widely used in the pharmaceutical industry as an intermediate for the synthesis of certain drugs.
The chemical is classified as a Pyrimidine and Benzoxazepine derivative and is known for its unique properties as a selective serotonin receptor agonist.

Upstream Products
The production of N-(2-Chloro-4-pyrimidinyl)-2,3-dimethyl-2H-indazol-6-amine begins with the synthesis of its upstream products, which include raw materials and intermediates required for the manufacture of the final product.

One of the key upstream products for the synthesis of Meta is 2,3-dimethyl-2H-indazol-6-amine, also known as 2,3-dimethyl-1H-indazole-6-amine (CAS No: 82578-23-1).
This compound is commonly synthesized using methods such as alkylation, Leuckart reaction, or Wolff-Kishner reduction.
2,3-dimethyl-2H-indazol-6-amine is then further processed to synthesize N-(2-chloro-4-pyrimidinyl)-2,3-dimethyl-2H-indazol-6-amine.

Downstream Products
The downstream products of Meta are the various drugs that are synthesized using this compound as an intermediate.
One of the most well-known drugs synthesized using Meta is the selective serotonin receptor agonist, Alzheimer's disease drug, and depression and anxiety treatment medicine, Agomelatine (CAS No: 162777-34-2).

Agomelatine is a synthetic compound that mimics the effects of the hormone melatonin in the body.
It is a selective agonist of the melatonin receptor type 1 and is used to treat sleep disorders, including insomnia and circadian rhythm disorders.
The drug is also used in the treatment of depression and anxiety disorders, particularly in cases where standard antidepressants have been ineffective.

Agomelatine is synthesized by combining several downstream intermediates, including Meta, phenylalanine, and tryptophan.
The synthesis of Agomelatine involves a series of chemical reactions, including alkylation, acylation, halogenation, nitration, sulfonation, and hydrolysis.

In conclusion, N-(2-Chloro-4-pyrimidinyl)-2,3-dimethyl-2H-indazol-6-amine, or Meta, is an important intermediate in the synthesis of several drugs, including Agomelatine, which is used to treat sleep disorders and depression.
The production of Meta begins with the synthesis of its upstream products, such as 2,3-dimethyl-2H-indazol-6-amine, and proceeds to the synthesis of downstream products, including Agomelatine and other drugs.
The manufacturing process for Meta and its downstream products involves a series of chemical reactions, including alkylation, acylation, halogenation, nitration, sulfonation, and hydrolysis.
The demand for Meta and its downstream products is expected to grow in the coming years as the pharmaceutical industry continues to develop new drugs to treat a wide range of medical conditions.