The world's first AIDS cure patient has died of a recurrence of cancer

, Sept. 30 (Xinhua Liu Qu) International
Association issued a statement on the 30th, known as the "Berlin patient" of the world's first cured
patient Timothy Brown has died of cancer recurrence.Adiba Kamaluzzaman, president of
International
Association, said: "We are very grateful to Timothy and his doctor, Gro Huttle, for opening the door for scientists to explore the concept that
can cure." For
months, Brown has been recovering from relapsed leukemia
and receiving hospice care at his home in Palm Springs, California, according to media reports.
, an American born in 1966, is recognized as the world's first
patient. He was diagnosed with acute myeloid leukemia
1995 while living in Berlin, Germany. Brown underwent radiation therapy and stem cell transplants in Berlin in 2007,
and leukemia disappeared.
Brown stopped
antiretroviral therapy shortly after the stem cell transplant and found no detectable
virus. In other words, he was cured. Brown's experience
that the disease could one day be curable. This has led to a
research and treatment of these diseases.
More than a decade after Brown's cure, adam Castilejo, an
patient known as the "London Patient," was not detected for a long time
after receiving a stem cell transplant, and is widely believed to be the second
patient to be cured.
common to treatment in two patients is that the CCR5 subject of stem cell donors has a rare mutation that makes the body resistant to the
virus, preventing it from reaching the host cells. CCR5 is
entry point for viruses to attack the human body. The researchers believe that replacing immune cells with cells without CCR5 receptors through stem cell transplantation may be the reason the
virus does not rebound in patients after discontinuation of treatment.
experts say that while Brown and Castilejo's treatment is not a viable strategy for a large-scale cure of
, it represents a
to find a cure.